![]() benzo[b]naphtho[1,2-d]thiophene structure
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Common Name | benzo[b]naphtho[1,2-d]thiophene | ||
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CAS Number | 205-43-6 | Molecular Weight | 234.316 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 434.3±14.0 °C at 760 mmHg | |
Molecular Formula | C16H10S | Melting Point | 185℃ (acetic acid ) | |
MSDS | N/A | Flash Point | 163.0±6.3 °C |
The predominant role of S-oxidation in rat liver metabolism of thiaarenes.
Cancer Lett. 32(1) , 107-16, (1986) Thiaarenes are metabolized by liver microsomes of untreated rats predominantly to sulfones and sulfoxides. After pretreatment of rats with monooxygenase inducers, ring oxidation of thiaarenes is also observed. In case of benzo[b]naphtho[2,3-d]thiophene the fo... |
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Towards β-selectivity in functional estrogen receptor antagonists.
Org. Biomol. Chem. 10(36) , 7334-46, (2012) Based on the benzo[b]naphtho[1,2-d]furan and benzo[b]naphtho[1,2-d]thiophene frameworks, a series of ligands with different basic side chains (BSCs) has been synthesized and pharmacologically evaluated. Also, their binding modes have been modelled using docki... |
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