Thymolphthalein

Thymolphthalein Structure
Thymolphthalein structure
Common Name Thymolphthalein
CAS Number 125-20-2 Molecular Weight 430.535
Density 1.2±0.1 g/cm3 Boiling Point 571.6±50.0 °C at 760 mmHg
Molecular Formula C28H30O4 Melting Point 251-253 °C(lit.)
MSDS Chinese USA Flash Point 187.5±23.6 °C

Thousands of chemical starting points for antimalarial lead identification.

Nature 465 , 305-10, (2010)

Malaria is a devastating infection caused by protozoa of the genus Plasmodium. Drug resistance is widespread, no new chemical class of antimalarials has been introduced into clinical practice since 1996 and there is a recent rise of parasite strains with redu...

Experimental correlation between the pKa value of sulfonphthaleins with the nature of the substituents groups.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 69(4) , 1235-45, (2008)

This work presents the results obtained from a spectrophotometry study performed on some indicators of the sulfonphtaleins like phenol red (PR), thymol blue (TB), bromothymol blue (BTB), xylenol orange (XO) and methylthymol blue (MTB). During the first stage ...

Analysis of nifedipine-acebutolol hydrochloride binary combination in tablets using UV-derivative spectroscopy, capillary gas chromatography and high performance liquid chromatography.

J. Pharm. Biomed. Anal. 16(1) , 21-30, (1997)

Three methods are described for the simultaneous determination of nifedipine and acebutolol hydrochloride in combined pharmaceutical tablets. The first method depends on first-derivative ultraviolet spectrophotometry, with peak-to-base and zero-crossing measu...

A new continuous spectrophotometric assay method for DOPA oxidase activity of tyrosinase.

J. Protein Chem. 22(5) , 473-80, (2003)

Sensitive assay methods for tyrosinase are essential not only for the understanding the process of pigment production but also for the development of effective inhibitors of tyrosinase. To develop an efficient assay method, we applied thymol blue to reaction ...

Method for prostatic acid phosphatase (PAP) with sodium thymolphthalein monophosphate (STMP) as substrate, as adapted to the Cobas Bio.

Clin. Chem. 32(8) , 1589-90, (1986)

Determination of the complexation constants of Pb(II) and Cd(II) with thymol blue using spectrophotometry, SQUAD and the HSAB principle.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 66(1) , 68-73, (2007)

This paper presents the results concerning the determination of the formation constants of the complexes between thymol blue, TB, and the metal ions Pb(II) or Cd(II). The experimental procedure was carried out in the presence of a nitrogen atmosphere at 25 de...

Simultaneous determination of copper, bismuth and lead by adsorptive stripping voltammetry in the presence of thymolphthalexone.

Anal. Sci. 22(7) , 955-9, (2006)

A novel, sensitive and selective adsorptive stripping procedure for simultaneous determination of copper, bismuth and lead is presented. The method is based on the adsorptive accumulation of thymolphthalexone (TPN) complexes of these elements onto a hanging m...

Incorporation of dyes into low density lipoprotein in the presence of non-ionic surfactants.

J. Pharm. Pharmacol. 41(12) , 858-60, (1989)

The interaction of low density lipoprotein (LDL) with two model dyes in the presence or absence of non-ionic surfactants has been studied. The water soluble dye, thymol blue, only weakly interacts with LDL to cause slight increases in particle size and the in...

Effects of presumptive test reagents on the ability to obtain restriction fragment length polymorphism (RFLP) patterns from human blood and semen stains.

J. Forensic Sci. 36(3) , 656-61, (1991)

Some of the commonly used presumptive test reagents for identification of blood and semen could potentially affect the recovery of intact high-molecular-weight deoxyribonucleic acid (DNA) from evidentiary samples. Thus, the capability of performing restrictio...

Evaluation of a hydrophilic ionic liquid as a salting-out phase separation agent to a water-tetrahydrofuran homogeneous system for aqueous biphasic extraction separation.

Anal. Sci. 28(6) , 541-3, (2012)

The use of a hydrophilic ionic liquid (IL), 1-butyl-3-methylimidazolium chloride (C(4)mimCl), as a salting-out phase separation agent to a water-tetrahydrofuran homogeneous system was studied for possible applications to novel aqueous biphasic extraction sepa...