1,4-Dichlorophthalazine
1,4-Dichlorophthalazine structure
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Common Name | 1,4-Dichlorophthalazine | ||
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| CAS Number | 4752-10-7 | Molecular Weight | 199.037 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 397.3±22.0 °C at 760 mmHg | |
| Molecular Formula | C8H4Cl2N2 | Melting Point | 160-162 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 226.4±7.9 °C | |
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Structure-activity studies and analgesic efficacy of N-(3-pyridinyl)-bridged bicyclic diamines, exceptionally potent agonists at nicotinic acetylcholine receptors.
J. Med. Chem. 50 , 3627, (2007) A series of exceptionally potent agonists at neuronal nicotinic acetylcholine receptors (nAChRs) has been investigated. Several N-(3-pyridinyl) derivatives of bridged bicyclic diamines exhibit double-digit-picomolar binding affinities for the alpha 4 beta 2 s... |
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Arylphthalazines. Part 2: 1-(Isoquinolin-5-yl)-4-arylamino phthalazines as potent inhibitors of VEGF receptors I and II.
Bioorg. Med. Chem. Lett. 16 , 1579, (2006) A novel class of 1-(isoquinolin-5-yl)-4-arylamino-phthalazines is described as inhibitors of vascular endothelial growth factor receptor II (VEGFR-2). Many compounds display VEGFR-2 inhibitory activity with an IC(50) as low as 0.017 microM in an HTRF enzymati... |
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Discrimination of reactively-dyed cotton fibres with thin layer chromatography and UV microspectrophotometry.
Sci. Justice 55 , 422-30, (2015) Reactively-dyed black, navy blue and medium red cotton samples showing metamerism under fluorescent tube illumination were examined. Optical microscopy (bright field, polarization and fluorescence microscopy) was used, followed by microspectrometry in the vis... |
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Synthesis of 4-aryl-1-(4-methylpiperazin-1-yl) phthalazines by Suzuki-type cross-coupling reaction. Guery S, et al.
Synthesis 2001(05) , 699-701, (2001)
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A simple and effective soluble polymer-bound ligand for the asymmetric dihydroxylation of olefins: DHQD-PHAL-OPEG-OMe. Kuang YQ, et al.
Tetrahedron Lett. 42(34) , 5925-5927, (2001)
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