MRS 1523

MRS 1523 Structure
MRS 1523 structure
Common Name MRS 1523
CAS Number 212329-37-8 Molecular Weight 399.54600
Density 1.1g/cm3 Boiling Point 551.3ºC at 760 mmHg
Molecular Formula C23H29NO3S Melting Point N/A
MSDS Chinese USA Flash Point 287.2ºC

Prostatic acid phosphatase reduces thermal sensitivity and chronic pain sensitization by depleting phosphatidylinositol 4,5-bisphosphate.

J. Neurosci. 30 , 10282-93, (2010)

Prostatic acid phosphatase (PAP) is expressed in nociceptive dorsal root ganglion (DRG) neurons, functions as an ectonucleotidase, and generates adenosine extracellularly. Here, we found that PAP inhibits noxious thermal sensitivity and sensitization that is ...

Structure-activity relationships and molecular modeling of 3, 5-diacyl-2,4-dialkylpyridine derivatives as selective A3 adenosine receptor antagonists.

J. Med. Chem. 41 , 3186, (1998)

The structure-activity relationships of 6-phenyl-1,4-dihydropyridine derivatives as selective antagonists at human A3 adenosine receptors have been explored (Jiang et al. J. Med. Chem. 1997, 39, 4667-4675). In the present study, related pyridine derivatives h...

A3 adenosine receptors regulate Cl- channels of nonpigmented ciliary epithelial cells.

Am. J. Physiol. 276 , C659, (1999)

Adenosine stimulates Cl- channels of the nonpigmented (NPE) cells of the ciliary epithelium. We sought to identify the specific adenosine receptors mediating this action. Cl- channel activity in immortalized human (HCE) NPE cells was determined by monitoring ...