NADPH (tetracyclohexanamine)

NADPH (tetracyclohexanamine) Structure
NADPH (tetracyclohexanamine) structure
Common Name NADPH (tetracyclohexanamine)
CAS Number 100929-71-3 Molecular Weight 1142.12000
Density N/A Boiling Point N/A
Molecular Formula C45H82N11O17P3 Melting Point N/A
MSDS USA Flash Point N/A

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets.

Nat. Rev. Drug Discov. 10 , 453-471, (2011)

NADPH oxidases are a family of enzymes that generate reactive oxygen species (ROS). The NOX1 (NADPH oxidase 1) and NOX2 oxidases are the major sources of ROS in the artery wall in conditions such as hypertension, hypercholesterolaemia, diabetes and ageing, an...

The role of free radical generation in increasing cerebrovascular permeability.

Free Radic. Biol. Med. 51 , 967-977, (2011)

The brain endothelium constitutes a barrier to the passive movement of substances from the blood into the cerebral microenvironment, and disruption of this barrier after a stroke or trauma has potentially fatal consequences. Reactive oxygen species (ROS), whi...

Alzheimer's disease and cholesterol: the fat connection.

Neurochem. Res. 32 , 739-750, (2007)

Since the discovery of the significance of the cholesterol-carrying apolipoprotein E and cholesterolaemia as major risk factors for Alzheimer's Disease (AD) there has been a mounting interest in the role of this lipid as a possible pathogenic agent. In this r...

Estrogen signaling and neuroprotection in cerebral ischemia. Brann D, Raz L, Wang R, et al.

J. Neuroendocrinol. 24(1) , 34-47, (2011)