Bisindolylmaleimide XI hydrochloride

Bisindolylmaleimide XI hydrochloride Structure
Bisindolylmaleimide XI hydrochloride structure
Common Name Bisindolylmaleimide XI hydrochloride
CAS Number 145333-02-4 Molecular Weight 489.01
Density N/A Boiling Point N/A
Molecular Formula C28H29ClN4O2 Melting Point N/A
MSDS USA Flash Point N/A

Inhibition of PTH desensitization by inhibition of the G protein-coupled receptor kinase-5 enzyme with Ro 32-0432. Moore, J.B., et al.

FASEB J. 12 , A741, (1998)

Isoenzyme specificity of bisindolylmaleimides, selective inhibitors of protein kinase C.

Biochem. J. 294 , 335-337, (1993)

The protein kinase C (PKC) family of isoenzymes is believed to mediate a wide range of signal-transduction pathways in many different cell types. A series of bisindolylmaleimides have been evaluated as inhibitors of members of the conventional PKC family (PKC...

Cardiorespiratory responses to systemic administration of a protein kinase C inhibitor in conscious rats.

J. Appl. Physiol. 84 , 641-648, (1998)

Although protein kinase C (PKC) is an essential component of multiple neurally mediated events, its role in respiratory control remains undefined. The ventilatory effects of a systemically active PKC inhibitor (Ro-32-0432; 100 mg/kg i.p.) were assessed by who...