16-Epiestriol

16-Epiestriol Structure
16-Epiestriol structure
Common Name 16-Epiestriol
CAS Number 547-81-9 Molecular Weight 288.38100
Density 1.255g/cm3 Boiling Point 469ºC at 760 mmHg
Molecular Formula C18H24O3 Melting Point 289-291ºC
MSDS USA Flash Point 220.8ºC

Associations of the fecal microbiome with urinary estrogens and estrogen metabolites in postmenopausal women.

J. Clin. Endocrinol. Metab. 99(12) , 4632-40, (2014)

The gut microbiota may influence the risk of breast cancer through effects on endogenous estrogens.The objective of the study was to investigate whether urinary estrogens and estrogen metabolites are associated with the diversity and composition of the fecal ...

Study of urinary steroid hormone disorders: difference between hepatocellular carcinoma in early stage and cirrhosis.

Anal. Bioanal. Chem 406(18) , 4325-35, (2014)

Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world. Discovery of novel biomarkers for early HCC from other liver diseases such as cirrhosis is of great clinical benefit. In this study, a novel steroid hormone metabolomic method based ...

Comparison of metabolic ratios of urinary estrogens between benign and malignant thyroid tumors in postmenopausal women.

BMC Clin. Pathol. 13 , 25, (2014)

Estrogen metabolism may be associated with the pathophysiological development of papillary thyroid carcinoma (PTC).To evaluate the differential estrogen metabolism between benign and malignant PTCs, estrogen profiling by gas chromatography-mass spectrometry w...

Association of Active and Sedentary Behaviors with Postmenopausal Estrogen Metabolism.

Med. Sci Sports Exerc. 48 , 439-48, (2016)

Physical activity may reduce endogenous estrogens, but few studies have assessed effects on estrogen metabolism and none have evaluated sedentary behavior in relation to estrogen metabolism. We assessed relationships between accelerometer-measured physical ac...

Concentration of endogenous estrogens and estrogen metabolites in the NCI-60 human tumor cell lines.

Genome Med. 4 , 31, (2012)

Endogenous estrogens and estrogen metabolites play an important role in the pathogenesis and development of human breast, endometrial, and ovarian cancers. Increasing evidence also supports their involvement in the development of certain lung, colon and prost...

The normal breast microenvironment of premenopausal women differentially influences the behavior of breast cancer cells in vitro and in vivo.

BMC Med. 8 , 27, (2010)

Breast cancer studies frequently focus on the role of the tumor microenvironment in the promotion of cancer; however, the influence of the normal breast microenvironment on cancer cells remains relatively unknown. To investigate the role of the normal breast ...

Relationship of serum estrogens and estrogen metabolites to postmenopausal breast cancer risk: a nested case-control study.

Breast Cancer Res. 15 , R34, (2014)

Elevated levels of circulating estrogens are linked to breast cancer risk among postmenopausal women but little is known about the importance of estrogen metabolism. A recently developed liquid chromatography tandem mass spectrometry-based method (LC-MS/MS) m...

Comparison of estrogens and estrogen metabolites in human breast tissue and urine.

Reprod. Biol. Endocrinol. 8 , 93, (2010)

An important aspect of the link between estrogen and breast cancer is whether urinary estrogen levels are representative of the intra-tissue levels of bioavailable estrogens.This study compares 15 estrogen and estrogen metabolite levels in breast tissue and u...