12-hydroxyoctadecanoic acid

12-hydroxyoctadecanoic acid Structure
12-hydroxyoctadecanoic acid structure
Common Name 12-hydroxyoctadecanoic acid
CAS Number 106-14-9 Molecular Weight 300.477
Density 0.9±0.1 g/cm3 Boiling Point 436.3±18.0 °C at 760 mmHg
Molecular Formula C18H36O3 Melting Point 80-81ºC
MSDS Chinese USA Flash Point 231.8±17.7 °C

Novel semisolid SNEDDS based on PEG-30-di-(polyhydroxystearate): Progesterone incorporation and in vitro digestion.

Int. J. Pharm. 486 , 77-87, (2015)

The aim of this work is to study the digestibility of PEG-30-di-(polyhydroxystearate) (Cithrol(®) DPHS) and its semisolid novel self-nanoemulsifying drug delivery systems (SNEDDS). Furthermore, the SNEDDS-mediated solubility enhancement of the poorly water-so...

Development of multifunctional lipid nanocapsules for the co-delivery of paclitaxel and CpG-ODN in the treatment of glioblastoma.

Int. J. Pharm. 495 , 972-80, (2015)

In this work, multifunctional lipid nanocapsules (M-LNC) were designed to combine the activity of the cytotoxic drug paclitaxel (PTX) with the immunostimulant CpG. This nanosystem, consisting of modified lipid nanocapsules coated with a cationic polymeric she...

Core-shell structured gel-nanocarriers for sustained drug release and enhanced antitumor effect.

Int. J. Pharm. 484(1-2) , 163-71, (2015)

The present paper attempted to develop temperature-sensitive and core-shell structured gel-nanocarriers (gel-NCs) for paclitaxel (PTX) with 12-hydroxystearic acid (12-HSA) as an organic gelator, which aims at sustaining drug release over time and thus improve...

Non-isothermal nucleation and crystallization of 12-hydroxystearic acid in vegetable oils. Rogers MA and Marangoni AG.

Cryst. Growth Des. 8(12) , 4596-4601, (2008)

A novel cryo-SEM technique for imaging vegetable oil based organogels. Rogers MA, et al.

J. Am. Oil Chem. Soc. 84(!0) , 899-906, (2007)

STM observation of 12-hydroxyoctadecanoic acid and its 4, 4'-bipyridinium salt self-assembled on a graphite surface Qian P, et al.

Chem. Commun. (Camb.) 13 , 1197-1198, (1999)