Atriopeptin II
Atriopeptin II structure
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Common Name | Atriopeptin II | ||
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| CAS Number | 89139-54-8 | Molecular Weight | 2386.63000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C98H156N34O32S2 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Purification and sequence analysis of bioactive atrial peptides (atriopeptins).
Science 223 , 67, (1984) Mammalian cardiac atria have several biologically active peptides that exert profound effects on sodium excretion, urine volume, and smooth muscle tone. In the present study two such peptides of low molecular weight were purified and separated from each other... |
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Epithelial modulation of the relaxant activity of atriopeptides in rat and guinea-pig tracheal smooth muscle.
Eur. J. Pharmacol. 212(2-3) , 187-94, (1992) Three peptide components of atrial natriuretic factor (ANF) caused relaxation of carbachol-contracted guinea-pig isolated tracheal smooth muscle. These were the 1-28, 5-28 and 5-27 peptide sequences (ANF(1-28), ANF-(5-28) and ANF-(5-27)). The peptides were 10... |
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[Atrial natriuretic peptides. III. Synthesis and biological activity of alpha-r-ANP, APII, APIII and des-Ser5,Ser6-APII].
Bioorg. Khim. 14(6) , 777-82, (1988) A series of atrial natriuretic peptides, viz., alpha-r-ANF, APII, APIII, and des-Ser5, Ser6-APII, have been obtained by condensation of earlier synthesized fragments promoted with complex F. Acetylaminomethyl protecting group were removed from cystein residue... |
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Characterization of atrial natriuretic peptide receptors in brain microvessel endothelial cells.
J. Cell Physiol. 146(1) , 43-51, (1991) Atrial natriuretic peptide (ANP) binding and ANP-induced increases in cyclic guanosine monophosphate (cGMP) levels have been observed in brain microvessels (Chabrier et al., 1987; Steardo and Nathanson, 1987), suggesting that this fluid-regulating hormone may... |
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Atriopeptin lowers aqueous humor formation and intraocular pressure and elevates ciliary cyclic GMP but lacks uveal vascular effects in the bovine perfused eye.
J. Ocul. Pharmacol. Ther. 13(1) , 1-11, (1997) The effects of atriopeptin (AP) on intraocular pressure (IOP), aqueous humor formation (AHF) and ciliary cyclic GMP in bovine eyes perfused in vitro through a ciliary artery were investigated. AHF was monitored fluorophotometrically by perfusing the anterior ... |