2,6-Dihydroxybenzoic acid
2,6-Dihydroxybenzoic acid structure
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Common Name | 2,6-Dihydroxybenzoic acid | ||
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| CAS Number | 303-07-1 | Molecular Weight | 154.120 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 343.7±32.0 °C at 760 mmHg | |
| Molecular Formula | C7H6O4 | Melting Point | 165 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | 175.8±21.6 °C | |
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Antimicrobial activity of natural products from the flora of Northern Ontario, Canada.
Pharm. Biol. 53(6) , 800-6, (2015) The number of multidrug resistant (MDR) microorganisms is increasing and the antimicrobial resistance expressed by these pathogens is generating a rising global health crisis. In fact, there are only a few antimicrobial agents left that can be used against MD... |
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Molecularly imprinted polymers with synthetic dummy template for simultaneously selective removal and enrichment of ginkgolic acids from Ginkgo biloba L. leaves extracts.
J. Chromatogr. A. 1368 , 44-51, (2014) Dummy molecularly imprinted polymers (DMIPs) for simultaneously selective removal and enrichment of ginkgolic acids (GAs) during the processing of Ginkgo biloba leaves have been prepared. Two dummy template molecule with similar structural skeleton to GAs, 6-... |
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Identifying chelators for metalloprotein inhibitors using a fragment-based approach.
J. Med. Chem. 54 , 591-602, (2011) Fragment-based lead design (FBLD) has been used to identify new metal-binding groups for metalloenzyme inhibitors. When screened at 1 mM, a chelator fragment library (CFL-1.1) of 96 compounds produced hit rates ranging from 29% to 43% for five matrix metallop... |
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Inhibition of 15-lipoxygenase-catalysed oxygenation of arachidonic acid by substituted benzoic acids.
Bioorg. Med. Chem. 16 , 4589-93, (2008) Elevated levels of phospholipases, prostaglandin synthases and lipoxygenases in colonic cells at various stages of malignancy indicate a strong link between dietary lipids and colon cancer. Lipoxygenase-catalysed arachidonic acid metabolism plays a key role i... |
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Short-column anion-exchange chromatography for soil and peat humic substances profiling by step-wise gradient of high pH aqueous sodium ethylenediaminetetraacetate.
J. Chromatogr. A. 1408 , 72-7, (2015) Novel anion-exchange liquid chromatographic method with step gradient of aqueous EDTA(4-) based mobile phase elution has been developed to profile available Slovak soil humic substances and alkaline extracts of various soils. The method utilize short glass co... |
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Bone selective effect of an estradiol conjugate with a novel tetracycline-derived bone-targeting agent.
Bioorg. Med. Chem. Lett. 19 , 680-3, (2009) In this study a novel bone-targeting agent containing elements of the tricarbonylmethane system of ring A of tetracycline was developed and was shown to bind to the mineral constituent of bone, hydroxyapatite. Conjugation of this bone-targeting agent to estra... |
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Crystal structures of nonoxidative zinc-dependent 2,6-dihydroxybenzoate (gamma-resorcylate) decarboxylase from Rhizobium sp. strain MTP-10005.
J. Biol. Chem. 281(45) , 34365-73, (2006) Reversible 2,6-dihydroxybenzoate decarboxylase from Rhizobium sp. strain MTP-10005 belongs to a nonoxidative decarboxylase family. We have determined the structures of the following three forms of the enzyme: the native form, the complex with the true substra... |
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Salicylate metabolites inhibit cyclooxygenase-2-dependent prostaglandin E(2) synthesis in murine macrophages.
Biochem. Biophys. Res. Commun. 274(1) , 197-202, (2000) The poor cyclooxygenase (COX) inhibitor and major aspirin metabolite salicylic acid is known to exert analgesic and anti-inflammatory effects by still unidentified mechanisms. In RAW 264.7 macrophages, lipopolysaccharide (LPS)-induced COX-2-dependent synthesi... |
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Reversible and nonoxidative gamma-resorcylic acid decarboxylase: characterization and gene cloning of a novel enzyme catalyzing carboxylation of resorcinol, 1,3-dihydroxybenzene, from Rhizobium radiobacter.
Biochem. Biophys. Res. Commun. 324(2) , 611-20, (2004) We found a gamma-resorcylic acid (gamma-RA, 2,6-dihydroxybenzoic acid) decarboxylase, as a novel enzyme applicable to carboxylation of resorcinol (RE, 1,3-dihydroxybenzene) to form gamma-RA, in a bacterial strain Rhizobium radiobacter WU-0108 isolated through... |
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Response of mixed microbial culture to 2,6-dihydroxybenzoic acid and peptone mixture at low sludge age--effect of culture history.
J. Environ. Sci. Health. A. Tox. Hazard. Subst. Environ. Eng. 45(7) , 875-82, (2010) The study evaluated the response of an enriched microbial culture on 2,6-dihydroxybenxoic acid (2,6-DHBA) and peptone mixture at low sludge age (theta(X)) under aerobic conditions. It emphasized the effect of culture history by comparing the response of the m... |