Fluticasone propionate
Fluticasone propionate structure
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Common Name | Fluticasone propionate | ||
|---|---|---|---|---|
| CAS Number | 80474-14-2 | Molecular Weight | 500.571 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 568.3±50.0 °C at 760 mmHg | |
| Molecular Formula | C25H31F3O5S | Melting Point | 275 °C | |
| MSDS | Chinese USA | Flash Point | 297.5±30.1 °C | |
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Environmental friendly method for urban wastewater monitoring of micropollutants defined in the Directive 2013/39/EU and Decision 2015/495/EU.
J. Chromatogr. A. 1418 , 140-9, (2015) The fate and removal of organic micropollutants in the environment is a demanding issue evidenced by the recent European policy. This work presents an analytical method for the trace quantification of 37 micropollutants including Priority Substances (Directiv... |
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A transgenic zebrafish model for monitoring glucocorticoid receptor activity.
Genes. Brain. Behav. 0 , (2014) Gene regulation resulting from glucocorticoid receptor and glucocorticoid response element interactions is a hallmark feature of stress response signaling. Imbalanced glucocorticoid production and glucocorticoid receptor activity have been linked to socioecon... |
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The use of hydrazine-based derivatization reagents for improved sensitivity and detection of carbonyl containing compounds using MALDI-MSI.
Anal. Bioanal. Chem 407(8) , 2085-94, (2015) Hydrazine-based derivatization reagents have been used to detect the presence of the carbonyl containing glucocorticoid fluticasone proprionate in rat lung tissue by MALDI-MSI. Such reagents also act as a matrix for analysis by MALDI-MS and have been termed "... |
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Human parainfluenza type 3 virus impairs the efficacy of glucocorticoids to limit allergy-induced pulmonary inflammation in guinea-pigs.
Clin. Sci. 125(10) , 471-82, (2013) Viral exacerbations of allergen-induced pulmonary inflammation in pre-clinical models reportedly reduce the efficacy of glucocorticoids to limit pulmonary inflammation and airways hyper-responsiveness to inhaled spasmogens. However, exacerbations of airway ob... |
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Cryptogenic stroke and small fiber neuropathy of unknown etiology in patients with alpha-galactosidase A -10T genotype.
Orphanet J. Rare Dis. 9 , 178, (2015) Fabry disease (FD) is a multisystemic disorder with typical neurological manifestations such as stroke and small fiber neuropathy (SFN), caused by mutations of the alpha-galactosidase A (GLA) gene. We analyzed 15 patients carrying the GLA haplotype -10C>T [rs... |
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Differential regulation of bladder cancer growth by various glucocorticoids: corticosterone and prednisone inhibit cell invasion without promoting cell proliferation or reducing cisplatin cytotoxicity.
Cancer Chemother. Pharmacol. 74(2) , 249-55, (2014) A synthetic glucocorticoid, dexamethasone, was recently shown to inhibit bladder cancer cell invasion and metastasis through the glucocorticoid receptor (GR) pathway but increased cell proliferation via inhibiting apoptosis particularly induced by cisplatin. ... |
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Association between TAAR6 polymorphisms and airway responsiveness to inhaled corticosteroids in asthmatic patients.
Pharmacogenet. Genomics 25 , 334-42, (2015) Genetic polymorphisms may be responsible for the wide variation in response to inhaled corticosteroids in asthmatic patients. We had previously reported that one polymorphism rs7772821, located on the 3'-UTR of trace amine-associated receptor 6 (TAAR6), is si... |
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Formulation pre-screening of inhalation powders using computational atom-atom systematic search method.
Mol. Pharm. 12(1) , 18-33, (2015) The synthonic modeling approach provides a molecule-centered understanding of the surface properties of crystals. It has been applied extensively to understand crystallization processes. This study aimed to investigate the functional relevance of synthonic mo... |
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Pneumonia and pneumonia related mortality in patients with COPD treated with fixed combinations of inhaled corticosteroid and long acting β2 agonist: observational matched cohort study (PATHOS).
BMJ 346 , f3306, (2013) To investigate the occurrence of pneumonia and pneumonia related events in patients with chronic obstructive pulmonary disease (COPD) treated with two different fixed combinations of inhaled corticosteroid/long acting β2 agonist.Observational retrospective pa... |
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Perception of bronchoconstriction: a complementary disease marker in children with asthma.
J. Asthma 50(6) , 560-4, (2013) Asthma guidelines use symptoms as the most important aspect of asthma control. Symptom perception varies widely between individuals. Over-perception as well as underperception of bronchoconstriction could have a negative effect on asthma management. We hypoth... |