NICOTINE DITARTRATE DIHYDRATE

NICOTINE DITARTRATE DIHYDRATE Structure
NICOTINE DITARTRATE DIHYDRATE structure
Common Name NICOTINE DITARTRATE DIHYDRATE
CAS Number 6019-06-3 Molecular Weight 498.43600
Density 1.38g/cm3 Boiling Point 469.8ºC at 760 mmHg
Molecular Formula C18H30N2O14 Melting Point 97-100ºC
MSDS N/A Flash Point 238ºC

The effect of varenicline on the development and expression of nicotine-induced behavioral sensitization and cross-sensitization in rats.

Addict. Biol. 20(2) , 248-58, (2015)

The present study focused on the evaluation of behavioral sensitization and cross-sensitization induced by nicotine and varenicline in rats. Furthermore, it examined the influence of varenicline, a partial alpha4beta2 nicotinic receptor agonist, on nicotine-i...

Nicotinic receptor subtype-selective circuit patterns in the subthalamic nucleus.

J. Neurosci. 35(9) , 3734-46, (2015)

The glutamatergic subthalamic nucleus (STN) exerts control over motor output through nuclei of the basal ganglia. High-frequency electrical stimuli in the STN effectively alleviate motor symptoms in movement disorders, and cholinergic stimulation boosts this ...

Nicotine exploits a COPI-mediated process for chaperone-mediated up-regulation of its receptors.

J. Gen. Physiol. 143(1) , 51-66, (2014)

Chronic exposure to nicotine up-regulates high sensitivity nicotinic acetylcholine receptors (nAChRs) in the brain. This up-regulation partially underlies addiction and may also contribute to protection against Parkinson's disease. nAChRs containing the α6 su...