1-Acetylguanidine
1-Acetylguanidine structure
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Common Name | 1-Acetylguanidine | ||
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| CAS Number | 5699-40-1 | Molecular Weight | 101.107 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 238.7ºC at 760mmHg | |
| Molecular Formula | C3H7N3O | Melting Point | 181-183ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 98.2ºC | |
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Novel 1H-imidazol-2-amine derivatives as potent and orally active vascular adhesion protein-1 (VAP-1) inhibitors for diabetic macular edema treatment.
Bioorg. Med. Chem. 21(13) , 3873-81, (2013) Novel thiazole derivatives were synthesized and evaluated as vascular adhesion protein-1 (VAP-1) inhibitors. Although we previously identified a compound (2) with potent VAP-1 inhibitory activity in rats, the human activity was relatively weak. Here, to impro... |
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Synthesis and biological evaluation of 4(5)-(6-alkylpyridin-2-yl)imidazoles as transforming growth factor-beta type 1 receptor kinase inhibitors.
J. Med. Chem. 50(13) , 3143-7, (2007) A series of 4(5)-(6-alkylpyridin-2-yl)imidazoles 13a-p, 17a, and 17b have been synthesized and evaluated for ALK5 inhibitory activity in an enzyme assay and in cell-based luciferase reporter assays. The quinoxalinyl analogue 13e inhibited ALK5 phosphorylation... |
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One-pot synthesis of N2-aminoprotected 6-substituted and cycloalka[d] 4-trifluoromethyl-2-acetylaminopyrimidines. Bonacorso HG, et al.
J. Heterocycl. Chem. 45(2) , 483-87, (2008)
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Bonacorso HG, et al.
Lett. Org. Chem. 4(7) , 495-99, (2007)
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Easy and regioselective access to dimethyl acetal-protected heterocycles and their efficient allylation reactions mediated by allylaluminum reagent. Bonacorso HG, et al.
ARKIVOC 4 , 291-305, (2013)
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