4-Methyl-L-leucine

4-Methyl-L-leucine Structure
4-Methyl-L-leucine structure
Common Name 4-Methyl-L-leucine
CAS Number 57224-50-7 Molecular Weight 145.199
Density 1.0±0.1 g/cm3 Boiling Point 226.1±23.0 °C at 760 mmHg
Molecular Formula C7H15NO2 Melting Point N/A
MSDS Chinese USA Flash Point 90.6±22.6 °C

The specificity and kinetic mechanism of branched-chain amino acid aminotransferase from Escherichia coli studied with a new improved coupled assay procedure and the enzyme's potential for biocatalysis.

FEBS J. 281(1) , 391-400, (2014)

Branched-chain amino acid aminotransferase (BCAT) plays a key role in the biosynthesis of hydrophobic amino acids (such as leucine, isoleucine and valine), and its substrate spectrum has not been fully explored or exploited owing to the inescapable restrictio...

Synthesis of gamma-methyl-L-leucine (neopentylglycine, Neo) and derivatives suitable for peptide synthesis.

Int. J. Pept. Protein Res. 18 , 249, (1981)

The modified Strecker synthesis of Patel & Worsley was combined with an enzymatic deamidation in the final step, to produce the title compound. The amino acid is a member of the family of the "fat" amino-acids with high lipophilicity and space-filling propert...