Amino(3-thienyl)acetic acid

Amino(3-thienyl)acetic acid Structure
Amino(3-thienyl)acetic acid structure
Common Name Amino(3-thienyl)acetic acid
CAS Number 38150-49-1 Molecular Weight 157.190
Density 1.4±0.1 g/cm3 Boiling Point 317.5±32.0 °C at 760 mmHg
Molecular Formula C6H7NO2S Melting Point 238℃
MSDS USA Flash Point 145.8±25.1 °C

Proton magnetic resonance studies of bradykinin antagonists.

Biopolymers 33 , 1237-1247, (1993)

Bradykinin (BK) is a peptide hormone with sequence Arg1-Pro2-Pro3-Gly4-Phe5-Ser6-Pro7-Phe8-Arg9 and has been implicated in a multitude of pathophysiological processes such as the ability to lower systemic blood pressure and stimulate pain. BK analogues having...

Design of P1' and P3' residues of trivalent thrombin inhibitors and their crystal structures.

Biochemistry 39 , 2384-2391, (2000)

Synthetic bivalent thrombin inhibitors comprise an active site blocking segment, a fibrinogen recognition exosite blocking segment, and a linker connecting these segments. Possible nonpolar interactions of the P1' and P3' residues of the linker with thrombin ...

Virtual fragment screening for novel inhibitors of 6-phosphogluconate dehydrogenase.

Bioorg. Med. Chem. 18 , 5056-62, (2010)

The enzyme 6-phosphogluconate dehydrogenase is a potential drug target for the parasitic protozoan Trypanosoma brucei, the causative organism of human African trypanosomiasis. This enzyme has a polar active site to accommodate the phosphate, hydroxyl and carb...