L-Lysine dihydrochloride

L-Lysine dihydrochloride Structure
L-Lysine dihydrochloride structure
Common Name L-Lysine dihydrochloride
CAS Number 657-26-1 Molecular Weight 219.109
Density N/A Boiling Point 311.5ºC at 760 mmHg
Molecular Formula C6H16Cl2N2O2 Melting Point 200-206 °C(lit.)
MSDS USA Flash Point 142.2ºC

iTRAQ-based analysis of progerin expression reveals mitochondrial dysfunction, reactive oxygen species accumulation and altered proteostasis.

Stem Cell Res. Ther. 6 , 119, (2015)

Nuclear accumulation of a mutant form of the nuclear protein Lamin-A, called Progerin (PG) or Lamin AΔ50, occurs in Hutchinson-Gilford Progeria Syndrome (HGPS) or Progeria, an accelerated aging disease. One of the main symptoms of this genetic disorder is a l...

Antioxidant and anti-inflammatory activities of Maillard reaction products isolated from sugar-amino acid model systems.

J. Agric. Food Chem. 59 , 11294-11303, (2011)

We investigated the antioxidant and anti-inflammatory activities of both crude and ultrafiltrated Maillard reaction (MR) products (MRPs) derived from sugar-amino acid MR models, comprising fructose (Fru), glucose (Glu) or ribose (Rib) reacted with glycine (Gl...

Determination of advanced glycation endproducts by LC-MS/MS in raw and roasted almonds (Prunus dulcis).

J. Agric. Food Chem. 59(22) , 12037-46, (2011)

A sensitive and reliable LC-(ESI)MS/MS method was developed and validated for the simultaneous analysis of five common advanced glycation endproducts (AGEs) after enzymatic digestion in raw and roasted almonds. AGEs included carboxymethyl-lysine (CML), carbox...

Moderate glycation of serum albumin affects folding, stability, and ligand binding.

Clin. Chim. Acta 412 , 2105-2116, (2011)

Serum protein glycation and formation of advanced glycation endproducts (AGE) correlates with diabetic complications. Highly AGE-modified albumin is frequently used to study the biochemical and cellular activities of AGE-proteins. However, moderately modified...

A novel type of lysine oxidase: L-lysine-epsilon-oxidase.

Biochim. Biophys. Acta 1764 , 1577-1585, (2006)

The melanogenic marine bacterium M. mediterranea synthesizes marinocine, a protein with antibacterial activity. We cloned the gene coding for this protein and named it lodA [P. Lucas-Elío, P. Hernández, A. Sanchez-Amat, F. Solano, Purification and partial cha...

Optical enzyme sensor for determining L-lysine content using L-lysine oxidase from the rockfish Sebastes schlegeli.

Anal. Bioanal. Chem 391 , 1255-1261, (2008)

L-lysine (L-Lys) in living bodies is critical for metabolism; therefore, determination of its levels in food is important. Most enzymatic methods for L-Lys analysis are performed using L-lysine oxidase (LyOx), but commercially manufactured LyOx is generally n...

Characterization of Liver Monocytic Myeloid-Derived Suppressor Cells and Their Role in a Murine Model of Non-Alcoholic Fatty Liver Disease.

PLoS ONE 11 , e0149948, (2016)

Myeloid-derived suppressor cells (MDSCs) are potent suppressors of T cell immunity in tumors and inflammatory diseases. They are identified by surface expression of CD11b+Gr1+ in mice, and CD11b+Gr1+ cells accumulate in the livers of obese mice. However, many...