H-Cys-Val-2-Nal-Met-OH

H-Cys-Val-2-Nal-Met-OH Structure
H-Cys-Val-2-Nal-Met-OH structure
Common Name H-Cys-Val-2-Nal-Met-OH
CAS Number 158022-12-9 Molecular Weight 548.71800
Density N/A Boiling Point N/A
Molecular Formula C26H36N4O5S2 Melting Point N/A
MSDS Chinese USA Flash Point N/A

Nonfarnesylated tetrapeptide inhibitors of protein farnesyltransferase.

J. Biol. Chem. 266 , 15575-15578, (1991)

The protein farnesyltransferase from rat brain was previously shown to be inhibited competitively by tetrapeptides that conform to the consensus Cys-A1-A2-X, where A1 and A2 are aliphatic amino acids and X is methionine, serine, or phenylalanine. In the curre...

Infectious tolerance via the consumption of essential amino acids and mTOR signaling.

Proc. Natl. Acad. Sci. U. S. A. 106 , 12055-60, (2009)

Infectious tolerance describes the process of CD4(+) regulatory T cells (Tregs) converting naïve T cells to become additional Tregs. We show that antigen-specific Tregs induce, within skin grafts and dendritic cells, the expression of enzymes that consume at ...

Hamilton, A.D. and Sebti, S.M

Drug News Perspect. 8 , 138, (1995)