Isophthalic acid
Isophthalic acid structure
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Common Name | Isophthalic acid | ||
|---|---|---|---|---|
| CAS Number | 121-91-5 | Molecular Weight | 166.131 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 412.3±28.0 °C at 760 mmHg | |
| Molecular Formula | C8H6O4 | Melting Point | 341-343 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 217.3±20.5 °C | |
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Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide.
PLoS ONE 10 , e0143161, (2015) Pyrrole-imidazole (Py-Im) polyamides are high affinity DNA-binding small molecules that can inhibit protein-DNA interactions. In VCaP cells, a human prostate cancer cell line overexpressing both AR and the TMPRSS2-ERG gene fusion, an androgen response element... |
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A neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy.
Blood 124(7) , 999-1009, (2014) Studies have endeavored to reconcile whether dysfunction of neutrophils in people with cystic fibrosis (CF) is a result of the genetic defect or is secondary due to infection and inflammation. In this study, we illustrate that disrupted function of the CF tra... |
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Regulatory volume increase in astrocytes exposed to hypertonic medium requires β1 -adrenergic Na(+) /K(+) -ATPase stimulation and glycogenolysis.
J. Neurosci. Res. 93(1) , 130-9, (2014) The cotransporter of Na(+) , K(+) , 2Cl(-) , and water, NKKC1, is activated under two conditions in the brain, exposure to highly elevated extracellular K(+) concentrations, causing astrocytic swelling, and regulatory volume increase in cells shrunk in respon... |
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Benzenepolycarboxylic acids with potential anti-hemorrhagic properties and structure–activity relationships
Bioorg. Med. Chem. 19 , 7000-2, (2011) Previously, we reported the structural requirements of the cinnamic acid relatives for inhibition of snake venom hemorrhagic action. In the present study, we examined the effect of benzenepolycarboxylic acids and substituted benzoic acids against Protobothrop... |
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C1 Domain-targeted isophthalate derivatives induce cell elongation and cell cycle arrest in HeLa cells.
PLoS ONE 6 , e20053, (2011) Diacylglycerol (DAG)-mediated signaling pathways, such as those mediated by protein kinase C (PKC), are central in regulating cell proliferation and apoptosis. DAG-responsive C1 domains are therefore considered attractive drug targets. Our group has designed ... |
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Separation of the isomers of benzene poly(carboxylic acid)s by quaternary ammonium salt via formation of deep eutectic solvents.
J. Phys. Chem. B 118(47) , 13646-50, (2014) Because of similar properties and very low volatility, isomers of benzene poly(carboxylic acid)s (BPCAs) are very difficult to separate. In this work, we found that isomers of BPCAs could be separated efficiently by quaternary ammonium salts (QASs) via format... |
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Migrating components in a polyurethane laminating adhesive identified using gas chromatography/mass spectrometry.
Rapid Commun. Mass Spectrom. 26(16) , 1810-6, (2012) Plastics are increasingly used as packaging materials for pharmaceuticals. However, diffusion of compounds in plastic into drugs may endanger patients' health. Regulatory authorities therefore demand detailed information about leachable compounds in plastics.... |
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Template induced structural isomerism and enhancement of porosity in manganese(II) based metal-organic frameworks (Mn-MOFs).
Chem. Commun. (Camb.) 47(27) , 7674-6, (2011) Three new metal-organic framework isomers have been synthesized by using the organic linker 5-triazole isophthalic acid and Mn(NO(3))(2)·xH(2)O. Structural conversions from non-porous to porous MOFs due to the template effect have been observed. The cross-sec... |
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Differences of crystal structure and dynamics between a soft porous nanocrystal and a bulk crystal.
Chem. Commun. (Camb.) 47(27) , 7632-4, (2011) We have demonstrated downsizing effects of the soft porous crystal, [Zn(isophthalate)(4,4'-bipyridyl)](n) (CID-1), on the adsorption behavior between CID-1 and CID-1 nanocrystal (NCID-1). The difference results from the packing crystal structures and the dyna... |
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Comparison of initial hydrolysis of the three dimethyl phthalate esters (DMPEs) by a basidiomycetous yeast, Trichosporon DMI-5-1, from coastal sediment.
Environ. Sci. Pollut. Res. Int. 18(9) , 1653-60, (2011) Dimethyl phthalate esters (DMPEs) are a group of plasticizers commonly detected in the environment with potential adverse human health impact. The degradation of DMPEs by fungal systems has been studied to a limited extent, particularly by yeasts. In this stu... |