Calcium phosphate

Calcium phosphate Structure
Calcium phosphate structure
Common Name Calcium phosphate
CAS Number 7758-87-4 Molecular Weight 310.177
Density 3.14 Boiling Point 158ºC at 760 mmHg
Molecular Formula Ca3O8P2 Melting Point 1670°C
MSDS Chinese USA Flash Point N/A

Oncogene-mediated regulation of p53 ISGylation and functions.

Oncotarget 5(14) , 5808-18, (2014)

Oncogene-mediated cellular transformation is a multistep process involving activation of growth-promoting pathways as well as inactivation of tumor suppressors. We recently found that ISGylation of the p53 tumor suppressor is an important novel mechanism to c...

Neuropilin 1 is an entry factor that promotes EBV infection of nasopharyngeal epithelial cells.

Nat. Commun. 6 , 6240, (2015)

Epstein-Barr virus (EBV) is implicated as an aetiological factor in B lymphomas and nasopharyngeal carcinoma. The mechanisms of cell-free EBV infection of nasopharyngeal epithelial cells remain elusive. EBV glycoprotein B (gB) is the critical fusion protein f...

Epigenetic variation in the Egfr gene generates quantitative variation in a complex trait in ants.

Nat. Commun. 6 , 6513, (2015)

Complex quantitative traits, like size and behaviour, are a pervasive feature of natural populations. Quantitative trait variation is the product of both genetic and environmental factors, yet little is known about the mechanisms through which their interacti...

Crosstalk between VEGF and MTA1 signaling pathways contribute to aggressiveness of breast carcinoma.

Mol. Carcinog. 54(5) , 333-50, (2015)

The expression of metastasis associated protein (MTA1) correlates well with tumor metastasis; however its role as a proangiogenic protein and the molecular mechanisms underlying the same are not fully understood. In this study the MTA1 protein was expressed a...

Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss.

Nat. Commun. 6 , 6651, (2015)

Immunglobulin G (IgG) sialylation represents a key checkpoint that determines the engagement of pro- or anti-inflammatory Fcγ receptors (FcγR) and the direction of the immune response. Whether IgG sialylation influences osteoclast differentiation and subseque...

SapC-DOPS nanovesicles induce Smac- and Bax-dependent apoptosis through mitochondrial activation in neuroblastomas.

Mol. Cancer 14 , 78, (2015)

High toxicity, morbidity and secondary malignancy render chemotherapy of neuroblastoma inefficient, prompting the search for novel compounds. Nanovesicles offer great promise in imaging and treatment of cancer. SapC-DOPS, a stable nanovesicle formed from the ...

Chronic mild stress and antidepressant treatment alter 5-HT1A receptor expression by modifying DNA methylation of a conserved Sp4 site.

Neurobiol. Dis. 82 , 332-41, (2015)

The serotonin 1A receptor (5-HT1A), a critical regulator of the brain serotonergic tone, is implicated in major depressive disorder (MDD) where it is often found to be dys-regulated. However, the extent to which stress and antidepressant treatment impact 5-HT...

Enhancing Protein Expression in HEK-293 Cells by Lowering Culture Temperature.

PLoS ONE 10(4) , e0123562, (2015)

Animal cells and cell lines, such as HEK-293 cells, are commonly cultured at 37°C. These cells are often used to express recombinant proteins. Having a higher expression level or a higher protein yield is generally desirable. As we demonstrate in this study, ...

Calcium and phosphate release from resin-based materials containing different calcium orthophosphate nanoparticles.

J. Biomed. Mater. Res. B. Appl. Biomater. 103 , 1670-8, (2015)

The study compared ion release from resin-based materials containing calcium orthophosphates. Amorphous calcium phosphate (ACP), dicalcium phosphate anhydrous (DCPA), dicalcium phosphate dihydrate (DCPD), and tricalcium phosphate (β-TCP) nanoparticles were ch...

Routes of Ca2+ Shuttling during Ca2+ Oscillations: FOCUS ON THE ROLE OF MITOCHONDRIAL Ca2+ HANDLING AND CYTOSOLIC Ca2+ BUFFERS.

J. Biol. Chem. 290 , 28214-30, (2015)

In some cell types, Ca(2+) oscillations are strictly dependent on Ca(2+) influx across the plasma membrane, whereas in others, oscillations also persist in the absence of Ca(2+) influx. We observed that, in primary mesothelial cells, the plasmalemmal Ca(2+) i...