Phosphoramidon disodium salt
Phosphoramidon disodium salt structure
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Common Name | Phosphoramidon disodium salt | ||
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| CAS Number | 119942-99-3 | Molecular Weight | 587.468 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H32N3Na2O10P | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Proteomic analysis of adult Ascaris suum fluid compartments and secretory products.
PLoS Negl. Trop. Dis. 8(6) , e2939, (2014) Strategies employed by parasites to establish infections are poorly understood. The host-parasite interface is maintained through a molecular dialog that, among other roles, protects parasites from host immune responses. Parasite excretory/secretory products ... |
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Endothelin-1 upregulation mediates aging-related cardiac fibrosis.
J. Mol. Cell. Cardiol. 80 , 101-9, (2015) Endothelin-1 (ET-1) plays a major role in regulating myocardial fibrosis in several pathological conditions, such as hypertension and diabetes. Aging is an independent risk factor for myocardial fibrosis. We hypothesized that ET-1 upregulation may be a basis ... |
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Structures and activities of protease inhibitors of microbial origin.
Meth. Enzymol. 45 , 678, (1976)
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Phosphoramidon modulates the number of endothelin receptors in cultured Swiss 3T3 fibroblasts.
Mol. Pharmacol. 44 , 422, (1993) Endothelin (ET) is generated from prepro-ET by dibasic pair proteolysis, followed by specific proteolytic cleavage between Trp21 and Val22. Currently, intense research efforts are focused on the investigation of a metalloprotease-like ET-converting enzyme tha... |
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Comparison of the cardiovascular and neural activity of endothelin-1, -2, -3 and respective proendothelins: effects of phosphoramidon and thiorphan.
Br. J. Pharmacol. 110 , 331, (1993) 1. In the anaesthetized, ganglion-blocked rat, intravenous boluses of endothelin-1, endothelin-2 and endothelin-3 induced a transient hypotensive effect followed by a potent long lasting pressor response (ED50 mmHg: 0.72 +/- 0.05, 1.8 +/- 0.2 and 2.7 +/- 0.3 ... |
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The relationships between enzyme inhibitors and function of mammalian cells.
Acta Biol. Med. Ger. 40 , 1523-1529, (1981) We have been searching for enzyme inhibitors in culture filtrates of microbes and have found leupeptin, antipain, chymostatin, elastatinal, pepstatin, hydroxypepstatin, pepstanone and phosphoramidon as specific inhibitors of serine, thiol, carboxyl and metall... |
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Evidence for phosphoramidon-sensitive cleavage of big endothelin-1 involved in endothelin-stimulated hepatic glucose production.
Regul. Pept. 51 , 207, (1994) Endothelin-1 (ET-1) is known to stimulate glycogenolysis in perfused rat livers and isolated rat hepatocytes. To determine the potential action of endothelin's precursor, big endothelin-1 (big ET-1), isolated rat livers were perfused with big ET-1 in a non-re... |
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Beynon, R.J. and Bond, J.S., ed.
Proteolytic Enzymes: A Practical Approach New York, NY , (1989), 246
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