5,6-Dimethoxy-1-indanone

5,6-Dimethoxy-1-indanone Structure
5,6-Dimethoxy-1-indanone structure
Common Name 5,6-Dimethoxy-1-indanone
CAS Number 2107-69-9 Molecular Weight 192.211
Density 1.2±0.1 g/cm3 Boiling Point 339.7±42.0 °C at 760 mmHg
Molecular Formula C11H12O3 Melting Point 118-122 ºC
MSDS Chinese USA Flash Point 150.4±14.3 °C

Thienylhalomethylketones: Irreversible glycogen synthase kinase 3 inhibitors as useful pharmacological tools

Bioorg. Med. Chem. 17 , 6914-25, (2009)

Thienylhalomethylketones, whose chemical, biological, and pharmaceutical data are here reported, are the first irreversible inhibitors of GSK-3beta described to date. Their inhibitory activity is likely related to the cysteine residue present in the ATP-bindi...

Ring-substituted 11-oxo-11H-indeno[1,2-b]quinoline-6-carboxamides with similar patterns of cytotoxicity to the dual topo I/II inhibitor DACA.

Bioorg. Med. Chem. 7(12) , 2801-9, (1999)

A series of ring-substituted analogues of the topoisomerase inhibitor 11-oxo-11H-indeno[1,2-b]quinoline-6-carboxamides was prepared and evaluated. The compounds were prepared by Pfitzinger reaction of the appropriate isatin-7-carboxylic acids and 1-indanones,...

Inhibition of bovine viral diarrhea virus RNA synthesis by thiosemicarbazone derived from 5,6-dimethoxy-1-indanone.

J. Virol. 85(11) , 5436-45, (2011)

In the present work, we described the activity of the thiosemicarbazone derived from 5,6-dimethoxy-1-indanone (TSC), which we previously characterized as a new compound that inhibits bovine viral diarrhea virus (BVDV) infection. We showed that TSC acts at a p...