N-Acetyl-L-leucine
N-Acetyl-L-leucine structure
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Common Name | N-Acetyl-L-leucine | ||
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| CAS Number | 1188-21-2 | Molecular Weight | 173.210 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 369.6±25.0 °C at 760 mmHg | |
| Molecular Formula | C8H15NO3 | Melting Point | 187-190 °C(lit.) | |
| MSDS | USA | Flash Point | 177.4±23.2 °C | |
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Shiftless nuclear magnetic resonance spectroscopy.
J. Chem. Phys. 128(5) , 052312, (2008) The acquisition and analysis of high resolution one- and two-dimensional solid-state nuclear magnetic resonance (NMR) spectra without chemical shift frequencies are described. Many variations of shiftless NMR spectroscopy are feasible. A two-dimensional exper... |
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Effects of vestibular training on motion sickness, nystagmus, and subjective vertical.
J. Vestib. Res. 17(5-6) , 227-37, (2007) Pitch head-and-trunk movements during constant velocity rotation are a provocative vestibular stimulus that produces vertigo and nausea. When exposed to this stimulus repeatedly, motion sickness symptoms diminish as the subjects habituate. Acetylleucine is a ... |
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Investigation of finite-pulse radiofrequency-driven recoupling methods for measurement of intercarbonyl distances in polycrystalline and membrane-associated HIV fusion peptide samples.
Magn. Reson. Chem. 45 Suppl 1 , S247-60, (2007) Two finite-pulse radiofrequency-driven recoupling (RFDR) methods were compared and applied to the measurement of 3-6 Å (13)CO-(13)CO distances in polycrystalline and membrane-associated HIV fusion peptide (HFP) samples. The RFDR methods were based on π pulses... |
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Autoradiography in brain of Macaca fascicularis monkeys after injection of acetyl-DL-leucine [2-14C] (Tanganil).
Eur. J. Drug Metab. Pharmacokinet. 26(1-2) , 71-6, (2001) Acetyl-DL-leucine [2-14C]: Tanganil a antivertigal drug has been injected intravenously in two macaca monkeys which have been sacrificed 2 and 5 minutes later. Radioactivity distribution has been studied by autoradiography in the brain. An important uptake of... |
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Peptide synthesis catalyzed by an antibody containing a binding site for variable amino acids.
Science 265 , 234, (1994) Monoclonal antibodies, induced with a phosphonate diester hapten, catalyzed the coupling of p-nitrophenyl esters of N-acetyl valine, leucine, and phenylalanine with tryptophan amide to form the corresponding dipeptides. All possible stereoisomeric combination... |
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[Effects of acetyl-DL-leucine on the recovery of the locomotor equilibrium and spontaneous discharge of lateral vestibular nucleus neurons in unilateral vestibular neurectomized cats].
Zhongguo Ying Yong Sheng Li Xue Za Zhi 13(3) , 257-60, (1997) The effects of acetyl-DL-leucine (AL) treatment (28 mg/kg.day, p.o.) on the vestibular compensation were studied over period of 6 weeks in unilateral vestibular neurectomized cats. This investigation was performed by measuring the recovery time of locomotor e... |
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A new method for identifying the amino acid attached to a particular RNA in the cell.
FEBS Lett. 381(3) , 195-8, (1996) To investigate the function of tRNAs or any other aminoacylable RNAs in vivo, it is important to be able to estimate the amounts and species of aminoacylated RNAs in living cells. We have developed a method of analyzing amino acids attached to particular tRNA... |
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Three-dimensional solid-state NMR experiment that correlates the chemical shift and dipolar coupling frequencies of two heteronuclei.
J. Magn. Reson. B 107(1) , 88-90, (1995)
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Direct evidence for modified solvent structure within the hydration shell of a hydrophobic amino acid.
Proc. Natl. Acad. Sci. U. S. A. 93(20) , 10769-74, (1996) Neutron scattering experiments are used to determine scattering profiles for aqueous solutions of hydrophobic and hydrophilic amino acid analogs. Solutions of hydrophobic solutes show a shift in the main diffraction peak to smaller angle as compared with pure... |
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A "magic sandwich" pulse sequence with reduced offset dependence for high-resolution separated local field spectroscopy.
J. Magn. Reson. 164(1) , 182-6, (2003) A pulse sequence for high resolution separated local field spectroscopy based on "magic sandwich" elements is demonstrated on a single crystal sample. Simulations and experimental results show that this pulse sequence has a reduced frequency offset dependence... |