3H-1,2-BENZODITHIOL-3-ONE

3H-1,2-BENZODITHIOL-3-ONE Structure
3H-1,2-BENZODITHIOL-3-ONE structure
Common Name 3H-1,2-BENZODITHIOL-3-ONE
CAS Number 1677-27-6 Molecular Weight 168.23600
Density N/A Boiling Point 337.6°C at 760 mmHg
Molecular Formula C7H4OS2 Melting Point 74-77 ℃(lit.)
MSDS Chinese USA Flash Point N/A

Use of 1,2,4-dithiazolidine-3,5-dione (DtsNH) and 3-ethoxy-1,2,4-dithiazoline-5-one (EDITH) for synthesis of phosphorothioate-containing oligodeoxyribonucleotides.

Nucleic Acids Res. 24(9) , 1602-7, (1996)

Previous methods for the preparation of phosphorothioate-containing oligodeoxyribonucleotides rely on the reaction of phosphite triesters with sulfurizing reagents such as tetraethylthiuram disulfide (TETD) and 3H-1,2-benzodithiol-3-one 1,1-dioxide (Beaucage ...

Possible chemical mechanisms underlying the antitumor activity of S-deoxyleinamycin.

Bioorg. Med. Chem. Lett. 18 , 3076-80, (2008)

Though less potent than the parent natural product leinamycin, S-deoxyleinamycin displays activity against human cancer cell lines that is comparable to many clinically used agents. The results reported here suggest that the 1,2-dithiolan-3-one heterocycle fo...

Novel syntheses of dithiosalicylide. Mitra K and Gates KS.

Tetrahedron Lett. 36(9) , 1391-94, (1995)

Nucleoside H-phosphonates. 13. Studies on 3H-1, 2-benzodithiol-3-one derivatives as sulfurizing reagents for H-phosphonate and H-phosphonothioate diesters. Stawinski J and Thelin M.

J. Org. Chem. 56(17) , 5169-5175, (1991)