6-Hydroxy-2-naphthoic acid

6-Hydroxy-2-naphthoic acid Structure
6-Hydroxy-2-naphthoic acid structure
Common Name 6-Hydroxy-2-naphthoic acid
CAS Number 16712-64-4 Molecular Weight 188.179
Density 1.4±0.1 g/cm3 Boiling Point 407.0±20.0 °C at 760 mmHg
Molecular Formula C11H8O3 Melting Point 240-250 °C(lit.)
MSDS Chinese USA Flash Point 214.1±18.3 °C

Novel Bradykinin Analogues Modified in the N-Terminal Part of the Molecule with a Variety of Acyl Substituents.

Int. J. Pept. Res. Ther. 18(2) , 117-124, (2012)

In the current work we present some pharmacological characteristics of ten new analogues of bradykinin (Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg) modified in the N-terminal part of the molecule with a variety of acyl substituents. Of the many acylating agents used...

Biocatalytic synthesis of dihydroxynaphthoic acids by cytochrome P450 CYP199A2.

Biosci. Biotechnol. Biochem. 73(12) , 2796-9, (2009)

CYP199A2, a bacterial P450 monooxygenase from Rhodopseudomonas palustris, was found to exhibit oxidation activity towards three hydroxynaphthoic acids. Whole cells of the recombinant Escherichia coli strain expressing CYP199A2 efficiently catalyzed the regios...

Co-crystals of caffeine and hydroxy-2-naphthoic acids: unusual formation of the carboxylic acid dimer in the presence of a heterosynthon.

Mol. Pharm. 4(3) , 339-46, (2007)

A group of caffeine-containing co-crystals of hydroxy-2-naphthoic acids were synthesized and analyzed via single-crystal X-ray diffraction and IR analysis. The imidazole-carboxylic acid synthon was observed in co-crystals involving 1-hydroxy-2-naphthoic and 3...

Hydroxynaphthoic acids identified in a high throughput screening potently ameliorate endoplasmic reticulum stress as novel chemical chaperones.

Chem. Pharm. Bull. 61(7) , 740-6, (2013)

Folding of newly synthesized protein occurs in endoplasmic reticulum (ER) and is assisted by chaperone molecules. In ER stress conditions, misfolded proteins are enriched in a lumen of ER perturbing its normal function, which triggers cellular self-defense me...

Synthesis and characterization of wholly aromatic polyesters derived from 6-hydroxy-5-phenyl-2-naphthoic acid or 4'-hydroxy-3'-phenylbiphenyl-4-carboxylic acid and 4-hydroxybenzoic acid. Huh S-M and Jin J.

Macromolecules 30(10) , 3005-3013, (1997)

New cholesteric liquid-crystal epoxy resins derived from 6-hydroxy-2-naphthoic acid. Espinosa MA, et al.

J. Polym. Sci. A Polym. Chem. 39(16) , 2847-58, (2001)