h-8 dihydrochloride
h-8 dihydrochloride structure
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Common Name | h-8 dihydrochloride | ||
|---|---|---|---|---|
| CAS Number | 113276-94-1 | Molecular Weight | 338.25300 | |
| Density | N/A | Boiling Point | 473.9ºC at 760 mmHg | |
| Molecular Formula | C12H17Cl2N3O2S | Melting Point | 221-222℃ (methanol water ) | |
| MSDS | USA | Flash Point | 240.4ºC | |
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Isoquinolinesulfonamides, novel and potent inhibitors of cyclic nucleotide dependent protein kinase and protein kinase C.
Biochemistry 23 , 5036-5041, (1984) Naphthalenesulfonamides such as N-(6-amino-hexyl)-5-chloro-1-naphthalenesulfonamide (W-7) are potent calmodulin (CaM) antagonists and act upon several protein kinases at higher concentration. When the naphthalene ring was replaced by isoquinoline, the derivat... |
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In vitro activation and nuclear translocation of NF-kappa B catalyzed by cyclic AMP-dependent protein kinase and protein kinase C.
Mol. Cell. Biol. 9 , 2424, (1989) We have examined whether a precursor form of NF-kappa B, a DNA-binding protein that plays a role in the transcriptional control of several genes, including kappa immunoglobulin light chain and interleukin-2 receptor alpha subunit, could be activated in vitro ... |
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