2-Thiophenecarboxamide
2-Thiophenecarboxamide structure
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Common Name | 2-Thiophenecarboxamide | ||
|---|---|---|---|---|
| CAS Number | 5813-89-8 | Molecular Weight | 127.16400 | |
| Density | 1.302g/cm3 | Boiling Point | 313.5ºC at 760 mmHg | |
| Molecular Formula | C5H5NOS | Melting Point | 181-183 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 143.4ºC | |
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A novel reaction mediated by human aldehyde oxidase: amide hydrolysis of GDC-0834.
Drug Metab. Dispos. 43 , 908-15, (2015) GDC-0834, a Bruton's tyrosine kinase inhibitor investigated as a potential treatment of rheumatoid arthritis, was previously reported to be extensively metabolized by amide hydrolysis such that no measurable levels of this compound were detected in human circ... |
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BDNF-TrkB signaling in the nucleus accumbens shell of mice has key role in methamphetamine withdrawal symptoms.
Transl. Psychiatry 5 , e666, (2015) Depression is a core symptom of methamphetamine (METH) withdrawal during the first several weeks of abstinence. However, the precise mechanisms underlying METH withdrawal symptoms remain unknown. Brain-derived neurotrophic factor (BDNF) and its specific recep... |
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Disruption of microtubules sensitizes the DNA damage-induced apoptosis through inhibiting nuclear factor κB (NF-κB) DNA-binding activity.
J. Korean Med. Sci. 25 , 1574-81, (2010) The massive reorganization of microtubule network involves in transcriptional regulation of several genes by controlling transcriptional factor, nuclear factor-kappa B (NF-κB) activity. The exact molecular mechanism by which microtubule rearrangement leads to... |