H-Ser-Glu-OH
H-Ser-Glu-OH structure
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Common Name | H-Ser-Glu-OH | ||
|---|---|---|---|---|
| CAS Number | 6403-16-3 | Molecular Weight | 234.20700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C8H14N2O6 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Studies on selection blockers. 5. Design, synthesis, and biological profile of sialyl Lewis x mimetics based on modified serine-glutamic acid dipeptides.
J. Med. Chem. 40 , 3534-3541, (1997) We have rationally designed a sLe(x) mimetic based on molecular modeling, synthesized type II and type II' beta-turn dipeptides (3a,b), and evaluated their biological profiles both in vitro and in vivo. Against E-selectin-sLe(x) binding, the type II beta-turn... |
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Carbohydrate mimetics and scaffolds: sweet spots in medicinal chemistry.
Future Med. Chem. 2 , 587-599, (2010) Several glycoprocessing enzymes and glycoreceptors have been recognized as important targets for therapeutic intervention. This concept has inspired the development of important classes of therapeutics, such as anti-influenza drugs inhibiting influenza virus ... |
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Studies on selectin blockers. 7. Structure-activity relationships of sialyl Lewis X mimetics based on modified Ser-Glu dipeptides.
J. Med. Chem. 41 , 4279-4287, (1998) We have previously found that heterochiral fucodipeptides, L-Ser-D-Glu (3a) and D-Ser-L-Glu (3b), exhibited up to 20-100 times more potency than a sialyl Lewis X (sLeX, 1) and a 3'-sulfated Lewis X analogue (2) toward E-selectin binding and have also proposed... |