Benzarone
Benzarone structure
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Common Name | Benzarone | ||
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| CAS Number | 1477-19-6 | Molecular Weight | 266.29100 | |
| Density | 1.234g/cm3 | Boiling Point | 473.6ºC at 760mmHg | |
| Molecular Formula | C17H14O3 | Melting Point | 124.3° | |
| MSDS | N/A | Flash Point | 240.2ºC | |
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Interactions of urate transporter URAT1 in human kidney with uricosuric drugs.
Nephrology (Carlton.) 16(2) , 156-62, (2011) Hyperuricaemia is a significant factor in a variety of diseases, including gout and cardiovascular diseases. The kidney plays a dominant role in maintaining plasma urate levels through the excretion process. Human renal urate transporter URAT1 is thought to b... |
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The EYA tyrosine phosphatase activity is pro-angiogenic and is inhibited by benzbromarone.
PLoS ONE 7(4) , e34806, (2012) Eyes Absents (EYA) are multifunctional proteins best known for their role in organogenesis. There is accumulating evidence that overexpression of EYAs in breast and ovarian cancers, and in malignant peripheral nerve sheath tumors, correlates with tumor growth... |
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[Effect of benzarone on the oxygen consumption and the mechanical activity of vascular smooth muscle].
Arzneimittelforschung 33(2) , 211-4, (1983) The influence of 2-ethyl-3-(4-hydroxy-benzoyl)-benzofurane (benzarone, Fragivic) on the energy metabolism of the wall of the rabbit common carotid artery and the rat portal vein was investigated by measuring the oxygen consumption of in vitro incubated vessel... |
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[On the site of action of benzarone and some other agents influencing the intracellular concentration of cyclic nucleotides].
Arzneimittelforschung 32(9) , 1114-20, (1982)
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[Drug modification of a risk factor of thrombosis in patients with varicosis].
Fortschr. Med. 100(30) , 1418-22, (1982)
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[Behavior of muscle tissue oxygen pressure in patients with severe intermittent claudication after oral administration of benzarone].
Med. Welt 34(9) , 273-4, (1983)
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[Benzarone for leg edema caused by chronic venous insufficiency].
MMW Munch. Med. Wochenschr. 125(16) , 343-4, (1983)
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Benzaron allergy.
Contact Dermatitis 11(2) , 122, (1984)
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Metabolic fate of the thrombolytic agent benzarone in man: comparison with the rat and dog.
Xenobiotica 17(7) , 881-96, (1987) 1. The metabolic fate of 14C-benzarone in the rat and dog has been compared to that in human subjects. An oral dose was well-absorbed in all three species. However, the 14C excretion patterns differed: humans (100 mg) excreted means of 73 and 19% dose in the ... |
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Effect of anti-inflammatory agents on the glycosaminoglycan metabolism in cultured human synovial cells.
Rheumatol. Int. 2(4) , 167-74, (1982)
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