1,2-dihexadecanoyl-rac-glycero-3-phosphoethanolamine
1,2-dihexadecanoyl-rac-glycero-3-phosphoethanolamine structure
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Common Name | 1,2-dihexadecanoyl-rac-glycero-3-phosphoethanolamine | ||
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| CAS Number | 5681-36-7 | Molecular Weight | 691.959 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 723.6±70.0 °C at 760 mmHg | |
| Molecular Formula | C37H74NO8P | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 391.4±35.7 °C | |
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Cytotoxic bile acids, but not cytoprotective species, inhibit the ordering effect of cholesterol in model membranes at physiologically active concentrations.
Biochim. Biophys. Acta 1828(9) , 2152-63, (2013) Submillimolar concentrations of cytotoxic bile acids (BAs) induce cell death via apoptosis. On the other hand, several cytoprotective BAs were shown to prevent apoptosis in the same concentration range. Still, the mechanisms by which BAs trigger these opposit... |
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Transient pearling and vesiculation of membrane tubes under osmotic gradients.
Faraday Discuss. 161 , 167-76; discussion 273-303, (2013) We report the experimental observation of osmotically induced transient pearling instabilities in vesicular membranes. Giant phospholipid vesicles subjected to negative osmotic gradient, which drives the influx of water in to the vesicular interior, produces ... |
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Interactions of N'-acetyl-rifabutin and N'-butanoyl-rifabutin with lipid bilayers: a synchrotron X-ray study.
Int. J. Pharm. 453(2) , 560-8, (2013) This work focuses on the interaction of N'-acetyl-rifabutin (RFB2) and N'-butanoyl-rifabutin (RFB3) with human and bacterial cell membrane models under physiological conditions. The effect of RFB2 and RFB3 on human cell membrane models was assessed using mult... |
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Targeting gemcitabine containing liposomes to CD44 expressing pancreatic adenocarcinoma cells causes an increase in the antitumoral activity.
Biochim. Biophys. Acta 1828(5) , 1396-404, (2013) Pancreatic adenocarcinoma is often diagnosed when metastatic events have occurred. The early spread of circulating cancer cells expressing the CD44 receptor may play a crucial role in this process. In this study, we have investigated the cellular delivery abi... |
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Phosphatidylethanolamine-lactose permease interaction: a comparative study based on FRET.
J. Phys. Chem. B 116(48) , 14023-8, (2012) In this work we have investigated the selectivity of lactose permease (LacY) of Escherichia coli (E. coli) for its surrounding phospholipids when reconstituted in binary mixtures of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine (POPE), 1,2-Palmitoyl-s... |
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Acyl chain differences in phosphatidylethanolamine determine domain formation and LacY distribution in biomimetic model membranes.
J. Phys. Chem. B 115(44) , 12778-84, (2011) Phosphatidylethanolamine (PE) and phosphatidylglycerol (PG) are the two main components of the inner membrane of Escherichia coli. It is well-known that inner membrane contains phospholipids with a nearly constant polar headgroup composition. However, bacteri... |
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Positron emission tomography imaging of the stability of Cu-64 labeled dipalmitoyl and distearoyl lipids in liposomes.
J. Control. Release 151(1) , 28-34, (2011) Changes in lipid acyl chain length can result in desorption of lipid from the liposomal anchorage and interaction with blood components. PET studies of the stability of such lipids have not been performed previously although such studies can map the pharmacok... |
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Structure of mixed phosphatidylethanolamine and cholesterol monolayers in a supported hybrid bilayer membrane studied by sum frequency generation vibrational spectroscopy.
J. Phys. Chem. B 115(20) , 6465-73, (2011) The structure of hybrid bilayer membranes (HBMs) containing either a pure cholesterol or mixed cholesterol/dipalmitoylphosphatidylethanolamine (DPPE) proximal layer adsorbed onto an octadecanethiol (ODT) self-assembled monolayer (SAM) on a gold substrate have... |
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Construction of amphiphilic copolymer nanoparticles based on hyperbranched Poly (Amine-Ester) and 1,2-Dipalmitoyl-Sn-Glycero-3-Phosphoethanolamine as drug carriers for cancer therapy
Nanomedicine: Nanotechnology, Biology, and Medicine 7(6) , 945-54, (2011) Novel amphiphilic copolymer nanoparticles (HPAE-co-PLA-DPPE) composed of hyperbranched poly (amine-ester), polylactide and 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE) segments were designed and synthesized that provided high encapsulation efficien... |
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Substrate suppression of thermal roughness in stacked supported bilayers.
Phys. Rev. E. Stat. Nonlin. Soft Matter Phys. 84(4 Pt 1) , 041914, (2011) We have fabricated a stack of five 1,2-dipalmitoyl-sn-3-phosphatidylethanolamine (DPPE) bilayers supported on a polished silicon substrate in excess water. The density profile of these stacks normal to the substrate was obtained through analysis of x-ray refl... |