Beta-Carotene
Beta-Carotene structure
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Common Name | Beta-Carotene | ||
|---|---|---|---|---|
| CAS Number | 7235-40-7 | Molecular Weight | 536.873 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 654.7±22.0 °C at 760 mmHg | |
| Molecular Formula | C40H56 | Melting Point | 178-179ºC | |
| MSDS | Chinese USA | Flash Point | 346.0±17.2 °C | |
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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Chem. Res. Toxicol. 23 , 171-83, (2010) Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental drug discovery projects toward safer medicines. In this st... |
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An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.
J. Nat. Prod. 73 , 1193-5, (2010) Antioxidants scavenge free radicals, singlet oxygen, and electrons in cellular redox reactions. The yellow MTT [3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium bromide] is reduced to a purple formazan by mitochondrial enzymes. NADPH is the basis of esta... |
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Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Toxicol. Mech. Methods 18 , 217-27, (2008) ABSTRACT Drug-induced phospholipidosis (PL) is a condition characterized by the accumulation of phospholipids and drug in lysosomes, and is found in a variety of tissue types. PL is frequently manifested in preclinical studies and may delay or prevent the dev... |
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Serum vitamin D, vitamin D binding protein, and lung cancer survival.
Lung Cancer 86(3) , 297-303, (2014) Vitamin D may prolong cancer survival by inhibiting tumor progression and metastasis, however, there are limited epidemiologic studies regarding the association between circulating 25-hydroxyvitamin D (25(OH)D) and lung cancer survival. The aim of this study ... |
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Relative vitamin A values of 9-cis- and 13-cis-β-carotene do not differ when fed at physiological levels during vitamin A depletion in Mongolian gerbils (Meriones unguiculatus).
Br. J. Nutr. 112(2) , 162-9, (2014) Provitamin A biofortification of staple crops may decrease the prevalence of vitamin A (VA) deficiency if widely adopted in target countries. To assess the impact of processing methods on the VA value of plant foods, the unique bioefficacies of cis-βC isomers... |
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Periodic root branching in Arabidopsis requires synthesis of an uncharacterized carotenoid derivative.
Proc. Natl. Acad. Sci. U. S. A. 111(13) , E1300-9, (2014) In plants, continuous formation of lateral roots (LRs) facilitates efficient exploration of the soil environment. Roots can maximize developmental capacity in variable environmental conditions through establishment of sites competent to form LRs. This LR prep... |
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Antioxidant vitamins and magnesium and the risk of hearing loss in the US general population.
Am. J. Clin. Nutr. 99(1) , 148-55, (2014) The protective effects of antioxidant vitamins on hearing loss are well established in animal studies but in few human studies. Recent animal studies suggest that magnesium intake along with antioxidants may act in synergy to prevent hearing loss.We examined ... |
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Improved tolerance of recombinant Escherichia coli to the toxicity of crude glycerol by overexpressing trehalose biosynthetic genes (otsBA) for the production of β-carotene.
Bioresour. Technol. 143 , 531-7, (2013) This study aims to investigate whether overexpressing the trehalose biosynthetic gene, otsBA operon, in β-carotene-producing recombinant Escherichia coli protects cells from toxic impurities in crude glycerol. The concentrations of potassium and methanol in c... |
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Comparative effects between fucoxanthinol and its precursor fucoxanthin on viability and apoptosis of breast cancer cell lines MCF-7 and MDA-MB-231.
Anticancer Res. 35(1) , 207-19, (2015) We evaluated whether low doses of the natural carotenoid fucoxanthin and/or of its metabolite fucoxanthinol are effective against proliferation of estrogen-sensitive MCF-7 and estrogen-resistant MDA-MB-231 breast cancer cell lines.These cell lines were stimul... |
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Self-report of fruit and vegetable intake that meets the 5 a day recommendation is associated with reduced levels of oxidative stress biomarkers and increased levels of antioxidant defense in premenopausal women.
J. Acad. Nutr. Diet. 113(6) , 776-85, (2013) Oxidative stress has been associated with a variety of chronic diseases and reproductive disorders. Fruits and vegetables (F/V) may contribute to antioxidant vitamin and micronutrient levels and reduce oxidative stress.To investigate the effect of meeting the... |