Resorufin methyl ether
Resorufin methyl ether structure
|
Common Name | Resorufin methyl ether | ||
|---|---|---|---|---|
| CAS Number | 5725-89-3 | Molecular Weight | 227.21500 | |
| Density | 1.33 g/cm3 | Boiling Point | 378.8ºC at 760 mmHg | |
| Molecular Formula | C13H9NO3 | Melting Point | ≥220ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 187.3ºC | |
|
Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2).
Arch. Toxicol. 89 , 1329-36, (2015) Small molecular weight protein kinase inhibitors are frequently used tools to unravel the complex network of cellular signal transduction under certain physiological and pathophysiological conditions. 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d... |
|
|
Sex-specific differences in hyperoxic lung injury in mice: role of cytochrome P450 (CYP)1A.
Toxicology 331 , 14-23, (2015) Sex-specific differences in pulmonary morbidity in adults and preterm infants are well documented. Hyperoxia contributes to lung injury in experimental animals and humans. Cytochrome P450 (CYP) 1A enzymes have been shown to play a mechanistic role in hyperoxi... |
|
|
Effect of commercially available green and black tea beverages on drug-metabolizing enzymes and oxidative stress in Wistar rats.
Food Chem. Toxicol. 70 , 120-7, (2014) The effect of commercially available green tea (GT) and black tea (BT) drinks on drug metabolizing enzymes (DME) and oxidative stress in rats was investigated. Male Wistar rats were fed a laboratory chow diet and GT or BT drink for 5 weeks. Control rats recei... |
|
|
Expression of aryl hydrocarbon receptor 1 (AHR1), AHR1 nuclear translocator 1 (ARNT1) and CYP1 family monooxygenase mRNAs and their activity in chicken ovarian follicles following in vitro exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD).
Toxicol. Lett. 237 , 100-11, (2015) The aim of this in vitro study was to determine the effect of TCDD and luteinizing hormone (LH) on mRNA expression of aryl hydrocarbon receptor 1 (AHR1), AHR1 nuclear translocator 1 (ARNT1), and the CYP1 family monooxygenases (CYP1A4, CYP1A5, CYP1B1), and to ... |
|
|
Modulation of aryl hydrocarbon receptor regulated genes by acute administration of trimethylarsine oxide in the lung, kidney and heart of C57BL/6 mice.
Xenobiotica 45 , 930-43, (2015) 1. Arsenite alters the expression of aryl hydrocarbon receptor (AhR)-regulated genes in extrahepatic tissues; yet, the effect of organic arsenicals still unknown. Therefore, C57BL/6 mice received trimethylarsine oxide (TMAO; 13 mg/kg i.p.) with or without 2,3... |
|
|
Biotransformation and Oxidative Stress Responses in Captive Nile Crocodile (Crocodylus niloticus) Exposed to Organic Contaminants from the Natural Environment in South Africa.
PLoS ONE 10 , e0130002, (2015) In the present study, the biotransformation and oxidative stress responses in relation to chemical burden in the liver of male and female Nile crocodiles--Crocodylus niloticus--from a commercial crocodile farm passively exposed to various anthropogenic aquati... |
|
|
The effect of cloudy apple juice on hepatic and mammary gland phase I and II enzymes induced by DMBA in female Sprague-Dawley rats.
Drug Chem. Toxicol. 37(4) , 472-9, (2014) Apples abundant in phenolic compounds show a variety of biological activities that may contribute to health beneficial effects against cardiovascular diseases, diabetes, obesity and cancer. We investigated the effect of cloudy apple juice (CAJ) on the hepatic... |
|
|
Disruption of cytochrome P4501A2 in mice leads to increased susceptibility to hyperoxic lung injury.
Free Radic. Biol. Med. 82 , 147-59, (2015) Hyperoxia contributes to acute lung injury in diseases such as acute respiratory distress syndrome. Cytochrome P450 (CYP) 1A enzymes have been implicated in hyperoxic lung injury, but the mechanistic role of CYP1A2 in pulmonary injury is not known. We hypothe... |
|
|
Transplantation of human adipose stem cell-derived hepatocyte-like cells with restricted localization to liver using acellular amniotic membrane.
Stem Cell Res. Ther. 6 , 217, (2015) Adult stem cell-derived hepatocytes transplantation holds considerable promise for future clinical individualized therapy of liver failure or dysfunction. However, the low engraftment of the available hepatocytes in the liver disease microenvironment has been... |
|
|
Variation in P450-mediated fenvalerate resistance levels is not correlated with CYP337B3 genotype in Chinese populations of Helicoverpa armigera.
Pestic. Biochem. Physiol. 121 , 129-35, (2015) Metabolic resistance to synthetic pyrethroids in Helicoverpa armigera has recently been associated with the chimeric cytochrome P450 enyzme CYP337B3. One variant of the latter, CYP337B3v1, accounts for 40-50 fold resistance to fenvalerate in an Australian p... |