EHT 1864
EHT 1864 structure
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Common Name | EHT 1864 | ||
|---|---|---|---|---|
| CAS Number | 754240-09-0 | Molecular Weight | 581.475 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C25H29Cl2F3N2O4S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Gq-mediated Akt translocation to the membrane: a novel PIP3-independent mechanism in platelets.
Blood 125(1) , 175-84, (2015) Akt is an important signaling molecule regulating platelet aggregation. Akt is phosphorylated after translocation to the membrane through Gi signaling pathways by a phosphatidylinositol-3,4,5-trisphosphate (PIP3)-dependent mechanism. However, Akt is more robu... |
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Instructive roles for cytokine-receptor binding parameters in determining signaling and functional potency.
Sci. Signal. 8 , ra114, (2015) Cytokines dimerize cell surface receptors to activate signaling and regulate many facets of the immune response. Many cytokines have pleiotropic effects, inducing a spectrum of redundant and distinct effects on different cell types. This pleiotropy has hamper... |
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An integrated imaging approach to the study of oxidative stress generation by mitochondrial dysfunction in living cells.
Environ. Health Perspect. 118 , 902-8, (2010) The mechanisms of action of many environmental agents commonly involve oxidative stress resulting from mitochondrial dysfunction. Zinc is a common environmental metallic contaminant that has been implicated in a variety of oxidant-dependent toxicological resp... |
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Ras-related C3 Botulinum Toxin Substrate (Rac) and Src Family Kinases (SFK) Are Proximal and Essential for Phosphatidylinositol 3-Kinase (PI3K) Activation in Natural Killer (NK) Cell-mediated Direct Cytotoxicity against Cryptococcus neoformans.
J. Biol. Chem. 291 , 6912-22, (2016) The activity of Rac in leukocytes is essential for immunity. However, its role in NK cell-mediated anti-microbial signaling remains unclear. In this study, we investigated the role of Rac in NK cell mediated anti-cryptococcal killing. We found thatCryptococcu... |