GANT58
GANT58 structure
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Common Name | GANT58 | ||
|---|---|---|---|---|
| CAS Number | 64048-12-0 | Molecular Weight | 392.476 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 414.1±40.0 °C at 760 mmHg | |
| Molecular Formula | C24H16N4S | Melting Point | N/A | |
| MSDS | USA | Flash Point | 169.0±17.7 °C | |
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Expression of the glioma-associated oncogene homolog 1 (gli1) in advanced serous ovarian cancer is associated with unfavorable overall survival.
PLoS ONE 8 , e60145, (2013) Recent evidence links aberrant activation of Hedgehog (Hh) signaling with the pathogenesis of several cancers including medulloblastoma, glioblastoma, melanoma as well as pancreas, colorectal, and prostate carcinomas. Here we investigated the role of the tran... |
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Targeting GLI1 expression in human inflammatory breast cancer cells enhances apoptosis and attenuates migration.
Br. J. Cancer 104 , 1575-86, (2011) Inflammatory breast cancer (IBC) is an aggressive subtype of breast cancer with distinct molecular profiles. Gene expression profiling previously identified sonic hedgehog (SHH) as part of a gene signature that is differentially regulated in IBC patients.The ... |
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