Hexamethonium bromide
Hexamethonium bromide structure
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Common Name | Hexamethonium bromide | ||
|---|---|---|---|---|
| CAS Number | 55-97-0 | Molecular Weight | 362.188 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H30Br2N2 | Melting Point | ~285 °C (dec.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Chemical genetics reveals a complex functional ground state of neural stem cells.
Nat. Chem. Biol. 3(5) , 268-273, (2007) The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain cancer. However, the complete repertoire of signaling pathways ... |
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A potentially novel nicotinic receptor in Aplysia neuroendocrine cells.
J. Neurophysiol. 112(2) , 446-62, (2014) Nicotinic receptors form a diverse group of ligand-gated ionotropic receptors with roles in both synaptic transmission and the control of excitability. In the bag cell neurons of Aplysia, acetylcholine activates an ionotropic receptor, which passes inward cur... |
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Changes in Nicotinic Neurotransmission during Enteric Nervous System Development.
J. Neurosci. 35 , 7106-15, (2015) Acetylcholine-activating pentameric nicotinic receptors (nAChRs) are an essential mode of neurotransmission in the enteric nervous system (ENS). In this study, we examined the functional development of specific nAChR subtypes in myenteric neurons using Wnt1-C... |
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VPAC1 receptors regulate intestinal secretion and muscle contractility by activating cholinergic neurons in guinea pig jejunum.
Am. J. Physiol. Gastrointest. Liver Physiol. 306(9) , G748-58, (2014) In the gastrointestinal tract, vasoactive intestinal peptide (VIP) is found exclusively within neurons. VIP regulates intestinal motility via neurally mediated and direct actions on smooth muscle and secretion by a direct mucosal action, and via actions on su... |
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Role of nitric oxide in the control of the gastric motility within the nucleus ambiguus of rats.
J. Physiol. Pharmacol. 63(6) , 623-9, (2012) This study aims to investigate whether exogenous nitric oxide (NO) plays a role in controlling gastric motility within the nucleus ambiguus (NA). Experiments were performed on male Wistar rats anaesthetized with chloral hydrate. A latex balloon, connected to ... |
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Activation of angiotensin II type 1 receptors and contractile activity in human sigmoid colon in vitro.
Acta Physiol. (Oxf.) 215 , 37-45, (2015) To analyse the effects of angiotensin II (Ang II) on the contractility of human sigmoid colon, and to characterize the subtype(s) of receptor(s) involved and the related action mechanism.The contractility of sigmoid colon circular muscle strips was recorded i... |
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Regulation of Cigarette Smoke Induction of IL-8 in Macrophages by AMP-activated Protein Kinase Signaling.
J. Cell Physiol. 230 , 1781-93, (2015) Inhaled cigarette smoke (CS) causes persistent lung inflammation in smokers. Interleukin 8 (IL-8) released from macrophages is a key chemokine during initiation and progression of CS-induced lung inflammation, yet its regulation is largely unknown. AMP-activa... |
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Rapid sensitization of physiological, neuronal, and locomotor effects of nicotine: critical role of peripheral drug actions.
J. Neurosci. 33(24) , 9937-49, (2013) Repeated exposure to nicotine and other psychostimulant drugs produces persistent increases in their psychomotor and physiological effects (sensitization), a phenomenon related to the drugs' reinforcing properties and abuse potential. Here we examined the rol... |
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Role of blood and vascular smooth muscle in the vasoactivity of nitrite.
Am. J. Physiol. Heart Circ. Physiol. 307(7) , H976-86, (2014) Recent evidence from humans and rats indicates that nitrite is a vasodilator under hypoxic conditions by reacting with metal-containing proteins to produce nitric oxide (NO). We tested the hypothesis that near-physiological concentrations of nitrite would pro... |
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Arylamine N-acetyl Transferase (NAT) in the blue secretion of Telescopium telescopium: xenobiotic metabolizing enzyme as a biomarker for detection of environmental pollution.
Springerplus 3 , 666, (2015) Telescopium telescopium, a marine mollusc collected from Sundarban mangrove, belongs to the largest mollusca phylum in the world and exudes a blue secretion when stimulated mechanically. The blue secretion was found to metabolize (preferentially) para-amino b... |