Cholecystokinin Octapeptide (desulfated)

Cholecystokinin Octapeptide (desulfated) Structure
Cholecystokinin Octapeptide (desulfated) structure
Common Name Cholecystokinin Octapeptide (desulfated)
CAS Number 25679-24-7 Molecular Weight 1063.21000
Density 1.387 g/cm3 Boiling Point 1496.8ºC at 760 mmHg
Molecular Formula C49H62N10O13S2 Melting Point N/A
MSDS Chinese USA Flash Point 859ºC

Cholecystokinin(CCK)-A and CCK-B/gastrin receptors in human tumors.

Cancer Res. 57 , 1377, (1997)

Cholecystokinin (CCK)-A and CCK-B/gastrin receptors were evaluated with in vitro receptor autoradiography in 406 human tumors of various origins using a sulfated 125I-labeled CCK decapeptide analogue 125I-(D-Tyr-Gly, Nle28,3l)-CCK 26-33 and 125I-labeled Leu15...

Protein kinase C-mediated inhibition of transmembrane signalling through CCK(A) and CCK(B) receptors.

Br. J. Pharmacol. 123 , 1189-1197, (1998)

1. The rat CCK(A) and CCK(B) receptors were stably expressed in Chinese hamster ovary (CHO-09) cells in order to compare modes of signal transduction and effects of protein kinase C (PKC) thereupon. 2. Spectrofluorophotometry of Fura-2-loaded cells revealed t...

Reciprocal effect of unsulfated and sulfated forms of cholecystokinin-octapeptide on gastric acid secretion in the rat.

Pharmacol. Res. 42 , 333-336, (2000)

The sulfated and unsulfated forms of cholecystokinin-octapeptide (CCK-8) were compared, with respect to their effect on gastric acid secretion, in the rat. Unsulfated CCK-8 stimulated acid secretion in a dose-dependent manner, while the sulfated form was with...

Characterization of cholecystokinin receptors on the human gallbladder.

Surgery 113(2) , 155-62, (1993)

Several studies examined in vivo and in vitro biologic activity of the human gallbladder in response to cholecystokinin (CCK). However, few studies have demonstrated directly the interaction of CCK with receptors on the human gallbladder, which is responsible...