(S)-AMPA(mM/ml)
(S)-AMPA(mM/ml) structure
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Common Name | (S)-AMPA(mM/ml) | ||
|---|---|---|---|---|
| CAS Number | 83643-88-3 | Molecular Weight | 186.165 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 425.6±45.0 °C at 760 mmHg | |
| Molecular Formula | C7H10N2O4 | Melting Point | 118-122 °C(lit.) | |
| MSDS | USA | Flash Point | 211.2±28.7 °C | |
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Nitrous oxide directly inhibits action potential-dependent neurotransmission from single presynaptic boutons adhering to rat hippocampal CA3 neurons.
Brain Res. Bull. 118 , 34-45, (2015) We evaluated the effects of N2O on synaptic transmission using a preparation of mechanically dissociated rat hippocampal CA3 neurons that allowed assays of single bouton responses evoked from native functional nerve endings. We studied the effects of N2O on G... |
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Differential expression and function of nicotinic acetylcholine receptors in subdivisions of medial habenula.
J. Neurosci. 34(29) , 9789-802, (2014) Neuronal nAChRs in the medial habenula (MHb) to the interpeduncular nucleus (IPN) pathway are key mediators of nicotine's aversive properties. In this paper, we report new details regarding nAChR anatomical localization and function in MHb and IPN. A new grou... |
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TARP γ-7 selectively enhances synaptic expression of calcium-permeable AMPARs.
Nat. Neurosci. 16(9) , 1266-74, (2013) Regulation of calcium-permeable AMPA receptors (CP-AMPARs) is crucial in normal synaptic function and neurological disease states. Although transmembrane AMPAR regulatory proteins (TARPs) such as stargazin (γ-2) modulate the properties of calcium-impermeable ... |
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Novel hypoglycemic injury mechanism: N-methyl-D-aspartate receptor-mediated white matter damage.
Ann. Neurol. 75(4) , 492-507, (2014) Hypoglycemia is a common adverse event and can injure central nervous system (CNS) white matter (WM). We determined whether glutamate receptors were involved in hypoglycemic WM injury.Mouse optic nerves (MON), CNS WM tracts, were maintained at 37°C with oxyge... |
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Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior.
J. Neurosci. 32(43) , 15124-32, (2012) We found previously that acute ex vivo as well as repeated cycles of in vivo ethanol exposure and withdrawal, including excessive voluntary consumption of ethanol, produces a long-lasting increase in the activity of NR2B-containing NMDA receptors (NR2B-NMDARs... |
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A subtype-specific function for the extracellular domain of neuroligin 1 in hippocampal LTP.
Neuron 76(2) , 309-16, (2012) At neuronal excitatory synapses, two major subtypes of the synaptic adhesion molecule neuroligin are present. These subtypes, neuroligin 1 and neuroligin 3, have roles in synaptogenesis and synaptic maintenance that appear largely overlapping. In this study, ... |
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In vivo recordings of GnRH neuron firing reveal heterogeneity and dependence upon GABAA receptor signaling.
J. Neurosci. 33(22) , 9394-401, (2013) The gonadotropin-releasing hormone (GnRH) neurons are the key cells regulating fertility in all mammalian species. The scattered distribution of these neurons has made investigation of their properties extremely difficult and the key goal of recording their e... |
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NGL-2 Regulates Input-Specific Synapse Development in CA1 Pyramidal Neurons
Neuron 76(4) , 762-75, (2012) An important organizing feature of the CNS is that individual neurons receive input from many different sources. Independent regulation of synaptic input is critical for the function and adaptive responses of the nervous system, but the underlying molecular m... |
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NMDAR-regulated dynamics of layer 4 neuronal dendrites during thalamocortical reorganization in neonates.
Neuron 82(2) , 365-79, (2014) Thalamocortical (TC) connectivity is reorganized by thalamic inputs during postnatal development; however, the dynamic characteristics of TC reorganization and the underlying mechanisms remain unexplored. We addressed this question using dendritic refinement ... |
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Synaptic potentiation in the nociceptive amygdala following fear learning in mice.
Mol. Brain 6 , 11, (2013) Pavlovian fear conditioning is a classical form of associative learning, which depends on associative synaptic plasticity in the amygdala. Recent findings suggest that the central amygdala (CeA) plays an active role in the acquisition of fear learning. Howeve... |