ZM 336372
ZM 336372 structure
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Common Name | ZM 336372 | ||
|---|---|---|---|---|
| CAS Number | 208260-29-1 | Molecular Weight | 389.447 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 484.4±45.0 °C at 760 mmHg | |
| Molecular Formula | C23H23N3O3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 246.8±28.7 °C | |
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Activation of protein kinase A (PKA) by 8-Cl-cAMP as a novel approach for antileukaemic therapy.
Br. J. Cancer 91 , 186-92, (2004) Activation of PKA by cAMP agonists, such as 8-Cl-cAMP activation, selectively causes rapid apoptosis in v-abl transformed fibroblasts by inhibiting the Raf-1 kinase. Here we investigated whether 8-Cl-cAMP is useful for the treatment of chronic myelogenous leu... |
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