1,2-Dilauroyl-sn-glycero-3-phosphocholine
1,2-Dilauroyl-sn-glycero-3-phosphocholine structure
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Common Name | 1,2-Dilauroyl-sn-glycero-3-phosphocholine | ||
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| CAS Number | 18194-25-7 | Molecular Weight | 621.83 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C32H64NO8P | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Membrane anchor of cytochrome P450 reductase suppresses the uncoupling of cytochrome P450.
Chem. Pharm. Bull. 63(4) , 286-94, (2015) Cytochrome P450 reductase (CPR) is an important redox partner of microsomal CYPs. CPR is composed of a membrane anchor and a catalytic domain that contains FAD and flavin mononucleotide (FMN) as redox centers and mediates electron transfer to CYP. Although th... |
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Phase coexistence in films composed of DLPC and DPPC: A comparison between different model membrane systems
Biochim. Biophys. Acta 1838(7) , 1823-31, (2014) For the biophysical study of membranes, a variety of model systems have been used to measure the different parameters and to extract general principles concerning processes that may occur in cellular membranes. However, there are very few reports in which the... |
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Biochemical characterization of Yarrowia lipolytica LIP8, a secreted lipase with a cleavable C-terminal region.
Biochim. Biophys. Acta 1851(2) , 129-40, (2015) Yarrowia lipolytica is a lipolytic yeast possessing 16 paralog genes coding for lipases. Little information on these lipases has been obtained and only the major secreted lipase, namely YLLIP2, had been biochemically and structurally characterized. Another se... |
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Effects of triglycerides on the hydrophobic drug loading capacity of saturated phosphatidylcholine-based liposomes.
Int. J. Pharm. 483(1-2) , 142-50, (2015) A high drug-loading capacity is a critical factor for the clinical development of liposomal formulations. The accommodation of hydrophobic drugs within the liposomal membrane is often limited in saturated phosphatidylcholine (PC)-based liposomes owing to the ... |
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Long-Acting Beta Agonists Enhance Allergic Airway Disease.
PLoS ONE 10 , e0142212, (2015) Asthma is one of the most common of medical illnesses and is treated in part by drugs that activate the beta-2-adrenoceptor (β2-AR) to dilate obstructed airways. Such drugs include long acting beta agonists (LABAs) that are paradoxically linked to excess asth... |
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Hydrolysis of mixed monomolecular films of tricaprylin/dilauroylphosphatidylcholine by lipase and phospholipase A₂.
Colloids Surf. B Biointerfaces 86(1) , 71-80, (2011) The purpose of this article was to describe the kinetics of the enzymatic action of one or more enzymes on mixture of substrates organized in 2D structures in order to mimic some situations existing in biological or industrial systems. Hydrolysis of the mixed... |
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Interactions between cytochromes P450 2B4 (CYP2B4) and 1A2 (CYP1A2) lead to alterations in toluene disposition and P450 uncoupling.
Biochemistry 52(23) , 4003-13, (2013) The goal of this study was to characterize the effects of CYP1A2·CYP2B4 complex formation on the rates and efficiency of toluene metabolism by comparing the results from simple reconstituted systems containing P450 reductase (CPR) and a single P450 to those u... |
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Unusual triskelion patterns and dye-labelled GUVs: consequences of the interaction of cholesterol-containing linear-hyperbranched block copolymers with phospholipids.
Soft Matter 11 , 6106-17, (2015) Cholesterol (Ch) linked to a linear-hyperbranched block copolymer composed of poly(ethylene glycol) (PEG) and poly(glycerol) (hbPG) was investigated for its membrane anchoring properties. Two polyether-based linear-hyperbranched block copolymers with and with... |
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Characterization of RNA-Like Oligomers from Lipid-Assisted Nonenzymatic Synthesis: Implications for Origin of Informational Molecules on Early Earth.
Life (Basel) 5 , 65-84, (2015) Prebiotic polymerization had to be a nonenzymatic, chemically driven process. These processes would have been particularly favored in scenarios which push reaction regimes far from equilibrium. Dehydration-rehydration (DH-RH) cycles are one such regime though... |
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Substrate Dependent Native Luminescence from Cytochromes P450 3A4, 2C9, and P450cam.
J. Phys. Chem. B 120 , 3038-47, (2016) Metalloporphyrin containing proteins, such as cytochrome P450, play a key role in biological systems. The spectroscopic properties of metalloporphyrins have been a subject of intense interest and intense debate for over 50 years. Iron-porphyrins are usually b... |