Myricitrin
Myricitrin structure
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Common Name | Myricitrin | ||
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| CAS Number | 17912-87-7 | Molecular Weight | 464.376 | |
| Density | 1.9±0.1 g/cm3 | Boiling Point | 896.6±65.0 °C at 760 mmHg | |
| Molecular Formula | C21H20O12 | Melting Point | 197 °C | |
| MSDS | Chinese USA | Flash Point | 315.7±27.8 °C | |
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Gallic acid functions as a TRPA1 antagonist with relevant antinociceptive and antiedematogenic effects in mice.
Naunyn Schmiedebergs Arch. Pharmacol. 387(7) , 679-89, (2014) The transient receptor potential ankyrin 1 (TRPA1) has been identified as a relevant target for the development of novel analgesics. Gallic acid (GA) is a polyphenolic compound commonly found in green tea and various berries and possesses a wide range of biol... |
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Chemical constituents of Indonesian plant Protium javanicum Burm. f. and their antifeedant activities against Coptotermes formosanus Shiraki.
Nat. Prod. Res. 27(3) , 270-3, (2013) In the continuing study of antifeedant compounds in Protium javanicum Burm. f. against Coptotermes formosanus Shiraki, 6-desacetylnimbin (1), quercitrin (2) and myricitrin (3) were isolated from P. javanicum extract. All compounds were characterised by NMR an... |
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Protective effects of myricitrin against osteoporosis via reducing reactive oxygen species and bone-resorbing cytokines.
Toxicol. Appl. Pharmacol. 280(3) , 550-60, (2014) Oxidative stress is a crucial pathogenic factor in the development of osteoporosis. Myricitrin, isolated from Myrica cerifera, is a potent antioxidant. We hypothesized that myricitrin possessed protective effects against osteoporosis by partially reducing rea... |
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Screening and biological evaluation of myricetin as a multiple target inhibitor insulin, epidermal growth factor, and androgen receptor; in silico and in vitro.
Invest. New Drugs 33 , 575-93, (2015) Myricetin is a naturally omnipresent benzo-α-pyrone flavonoids derivative; has potent anticancer activity. Receptor tyrosine kinases family provides the decisive role in cancer initiation and progression. These receptors have recently caught the attention of ... |
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Myricitrin as a substrate and inhibitor of myeloperoxidase: implications for the pharmacological effects of flavonoids.
Free Radic. Biol. Med. 44(1) , 109-20, (2008) Flavonoids are increasingly being ingested by the general population as chemotherapeutic and anti-inflammatory agents. They are potentially toxic because of their conversion to free radicals and reactive quinones by peroxidases. Little detailed information is... |
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Analysis of the antinociceptive effect of the flavonoid myricitrin: evidence for a role of the L-arginine-nitric oxide and protein kinase C pathways.
J. Pharmacol. Exp. Ther. 316(2) , 789-96, (2006) The present study investigated the antinociceptive effects of the flavonoid myricitrin in chemical behavioral models of pain in mice and rats. Myricitrin given by i.p. or p.o. routes produced dose-related antinociception when assessed on acetic acid-induced v... |
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Inhibitory effects of myricitrin on oxidative stress-induced endothelial damage and early atherosclerosis in ApoE-/- mice.
Toxicol. Appl. Pharmacol. 271(1) , 114-26, (2013) Atherosclerosis (AS) is a state of heightened oxidative stress characterized by lipid and protein oxidation in vascular walls. Oxidative stress-induced vascular endothelial cell (VEC) injury is a major factor in the pathogenesis of AS. Myricitrin, a natural f... |
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Anti-allodynic property of flavonoid myricitrin in models of persistent inflammatory and neuropathic pain in mice.
Biochem. Pharmacol. 72(12) , 1707-13, (2006) The aim of the present study was to investigate the effects of myricitrin, a flavonoid with anti-inflammatory and antinociceptive action, upon persistent neuropathic and inflammatory pain. The neuropathic pain was caused by a partial ligation (2/3) of the sci... |
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The diarylheptanoid (+)-aR,11S-myricanol and two flavones from bayberry (Myrica cerifera) destabilize the microtubule-associated protein tau.
J. Nat. Prod. 74(1) , 38-44, (2011) Target-based drug discovery for Alzheimer's disease (AD) centered on modulation of the amyloid β peptide has met with limited success. Therefore, recent efforts have focused on targeting the microtubule-associated protein tau. Tau pathologically accumulates i... |
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Myricitrin protects against peroxynitrite-mediated DNA damage and cytotoxicity in astrocytes.
Food Chem. 141(2) , 927-33, (2013) Peroxynitrite, a potent oxidising and nitrating species, has been implicated in the pathogenesis of neurodegenerative diseases. This study was undertaken to investigate the protective effect of myricitrin on peroxynitrite-mediated toxicity and the underlying ... |