(-)-Epigallocatechin(EGC)

(-)-Epigallocatechin(EGC) Structure
(-)-Epigallocatechin(EGC) structure
Common Name (-)-Epigallocatechin(EGC)
CAS Number 970-74-1 Molecular Weight 306.267
Density 1.7±0.1 g/cm3 Boiling Point 685.6±55.0 °C at 760 mmHg
Molecular Formula C15H14O7 Melting Point 208-210°C
MSDS Chinese USA Flash Point 368.5±31.5 °C

Effects of malted and non-malted whole-grain wheat on metabolic and inflammatory biomarkers in overweight/obese adults: a randomised crossover pilot study.

Food Chem. 194 , 495-502, (2015)

Metabolic dysfunction in obesity may be attenuated by whole-grain intake, which has been attributed to synergistic actions of bioactive compounds. Germination/malting may increase grain bioactives, including polyphenols, however biological effects compared wi...

A colourimetric sensor for the simultaneous determination of oxidative status and antioxidant activity on the same membrane: N,N-dimethyl-p-phenylene diamine (DMPD) on Nafion.

Anal. Chim. Acta 865 , 60-70, (2015)

A colourimetric sensor capable of simultaneously measuring oxidative status (OS) in terms of the hazard produced by reactive oxygen species (ROS) and antioxidant activity (AOA) in regard to ROS-scavenging ability of antioxidant compounds was developed. The co...

Identification and quantification of phytochemicals in nutraceutical products from green tea by UHPLC-Orbitrap-MS.

Food Chem. 173 , 607-18, (2014)

A method has been developed and validated for the simultaneous detection and quantification of phytochemicals in nutraceutical products obtained from green tea. For that purpose, ultra-high performance liquid chromatography coupled to single-stage Orbitrap hi...

Production of an anthocyanin-rich food colourant from Thymus moroderi and its application in foods.

J. Sci. Food Agric. 95(6) , 1283-93, (2015)

Anthocyanins and other polyphenols from flowers and bracts of Thymus sp. are studied. An anthocyanin-rich food colourant with interesting high antioxidant activity from Thymus moroderi has been obtained, and applied to colour foods.Anthocyanins and other poly...

Comparative proteomic analysis using 2DE-LC-MS/MS reveals the mechanism of Fuzhuan brick tea extract against hepatic fat accumulation in rats with nonalcoholic fatty liver disease.

Electrophoresis 36 , 2002-16, (2015)

Fuzhuan brick tea has received increasing attention in recent years owing to its benefits for nonalcoholic fatty liver disease (NAFLD) and associated metabolic syndrome. For exploring the ameliorative mechanism, the liver proteomes from three groups of rats f...

Radical-scavenging activity of dietary phytophenols in combination with co-antioxidants using the induction period method.

Molecules 16(12) , 10457-70, (2011)

The radical-scavenging activity of dietary phytophenols has been investigated by many researches due to their antioxidant, anti-inflammatory and anticancer property but the radical-scavenging effect of 2-phytophenol and the phytophenol:co-antioxidants, vitami...

Extraction Kinetics of phytochemicals and antioxidant activity during black tea (Camellia sinensis L.) brewing.

Nutr. J. 14 , 74, (2015)

Tea is the most consumed beverage in the world which is second only to water. Tea contains a broad spectrum of active ingredients which are responsible for its health benefits. The composition of constituents extracted to the tea brew depends on the method of...

Development and validation of UHPLC-MS/MS method for determination of eight naturally occurring catechin derivatives in various tea samples and the role of matrix effects.

J. Pharm. Biomed. Anal. 114 , 62-70, (2015)

A complete analytical procedure combining optimized tea infusion preparation and validated UHPLC-MS/MS method was developed for routine quantification of eight naturally occurring catechin derivatives in various tea samples. The preparation of tea infusions w...

Theaflavins enhance intestinal barrier of Caco-2 Cell monolayers through the expression of AMP-activated protein kinase-mediated Occludin, Claudin-1, and ZO-1.

Biosci. Biotechnol. Biochem. 79(1) , 130-7, (2015)

We investigated the effect of theaflavins (TFs) on membrane barrier of Caco-2 cells. For fluorescein-transport experiments, the apparent permeability (Papp) of fluorescein in Caco-2 cells pretreated with 20 μM TFs were significantly decreased compared with th...

Isolation and characterization of rat intestinal bacteria involved in biotransformation of (-)-epigallocatechin.

Arch. Microbiol. 196(10) , 681-95, (2014)

Two intestinal bacterial strains MT4s-5 and MT42 involved in the degradation of (-)-epigallocatechin (EGC) were isolated from rat feces. Strain MT4s-5 was tentatively identified as Adlercreutzia equolifaciens. This strain converted EGC into not only 1-(3, 4, ...