Iohexol
Iohexol structure
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Common Name | Iohexol | ||
|---|---|---|---|---|
| CAS Number | 66108-95-0 | Molecular Weight | 821.138 | |
| Density | 2.2±0.1 g/cm3 | Boiling Point | 891.5±65.0 °C at 760 mmHg | |
| Molecular Formula | C19H26I3N3O9 | Melting Point | 254-2560C | |
| MSDS | Chinese USA | Flash Point | 493.0±34.3 °C | |
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Construction of a biocompatible decellularized porcine hepatic lobe for liver bioengineering.
Int. J. Artif. Organs 38 , 96-104, (2015) One of the major obstacles in applying decellularized organs for clinical use is the recellularization step, during which huge numbers of cells are required to develop whole livers. We established a simple protocol for constructing a bioartificial hepatic lob... |
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Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Chem. Res. Toxicol. 23 , 171-83, (2010) Drug-induced liver injury is one of the main causes of drug attrition. The ability to predict the liver effects of drug candidates from their chemical structures is critical to help guide experimental drug discovery projects toward safer medicines. In this st... |
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Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
J. Sci. Ind. Res. 65(10) , 808, (2006) Drug-induced liver injury (DILI) is a significant concern in drug development due to the poor concordance between preclinical and clinical findings of liver toxicity. We hypothesized that the DILI types (hepatotoxic side effects) seen in the clinic can be tra... |
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Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Eur. J. Med. Chem. 46 , 218-28, (2011) In order to minimize the high attrition rate that usually characterizes drug research and development projects, current medicinal chemists aim to characterize both pharmacological and ADME profiles at the beginning of drug R&D initiatives. Thus, the developme... |
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Corticosteroid injection of the arthritic hip: what is the indication?
Scott. Med. J. 60(1) , 29-31, (2015) Forty-four patients who had image-guided corticosteroid injection of the hip were reviewed as part of a service improvement project to ascertain the medium term benefit of the procedure. Injections were indicated for treatment of hip pain or as part of a diag... |
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Comparison of combination therapy of high-dose oral N-acetylcysteine and intravenous sodium bicarbonate hydration with individual therapies in the reduction of Contrast-induced Nephropathy during Cardiac Catheterisation and Percutaneous Coronary Intervention (CONTRAST): A multi-centre, randomised, controlled trial.
Int. J. Cardiol. 201 , 237-42, (2015) N-acetylcysteine (NAC) and sodium bicarbonate (SOB) therapies may prevent contrast-induced nephropathy (CIN). However, the efficacy of using combination over individual therapies was not established, and there was no large randomised study comparing abbreviat... |
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Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Drug Metab. Dispos. 36 , 1385-405, (2008) We present herein a compilation and trend analysis of human i.v. pharmacokinetic data on 670 drugs representing, to our knowledge, the largest publicly available set of human clinical pharmacokinetic data. This data set provides the drug metabolism scientist ... |
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Rapid determination of X-ray contrast agent iomeprol in human plasma by on-line solid-phase extraction coupled with phase optimized liquid chromatography.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 992 , 14-22, (2015) Phase optimized liquid chromatography (POPLC) allows for the optimized combination of column segments of any length and stationary phases with different functionalities. In this study, a simple and rapid method using POPLC coupled with on-line solid-phase ext... |
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Promoting endothelial recovery and reducing neointimal hyperplasia using sequential-like release of acetylsalicylic acid and paclitaxel-loaded biodegradable stents.
Int. J. Nanomedicine 9 , 4117-33, (2014) This work reports on the development of a biodegradable dual-drug-eluting stent with sequential-like and sustainable drug-release of anti-platelet acetylsalicylic acid and anti-smooth muscle cell (SMC) proliferative paclitaxel.To fabricate the biodegradable s... |
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Solid-phase extraction coupled with ultra high performance liquid chromatography and electrospray tandem mass spectrometry for the highly sensitive determination of five iodinated X-ray contrast media in environmental water samples.
J. Sep. Sci. 38 , 1998-2005, (2015) A highly sensitive method based on solid-phase extraction and ultra high performance liquid chromatography with electrospray tandem mass spectrometry has been developed for simultaneous determination of five iodinated X-ray contrast media in environmental wat... |