N-Butanoyl-DL-homoserine lactone
N-Butanoyl-DL-homoserine lactone structure
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Common Name | N-Butanoyl-DL-homoserine lactone | ||
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| CAS Number | 98426-48-3 | Molecular Weight | 171.19400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C8H13NO3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Quorum sensing and Chromobacterium violaceum: exploitation of violacein production and inhibition for the detection of N-acylhomoserine lactones.
Microbiology 143 , 3703, (1997) Quorum sensing relies upon the interaction of a diffusible signal molecule with a transcriptional activator protein to couple gene expression with cell population density. In Gram-negative bacteria, such signal molecules are usually N-acylhomoserine lactones ... |
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Detection of acyl-homoserine lactones by Escherichia and Salmonella.
Curr. Opin. Microbiol. 14 , 188-193, (2011) Escherichia and Salmonella do not synthesize quorum-sensing signaling molecules of the N-acyl-l-homoserine lactone (AHL) type but they can detect AHLs produced by other species of bacteria. AHLs are present in the bovine rumen but not in the remainder of the ... |
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N-acyl homoserinelactone-mediated gene regulation in gram-negative bacteria.
Syst. Appl. Microbiol. 22 , 493-506, (1999) The view of bacteria as unicellular organisms has strong roots in the tradition of culturing bacteria in liquid media. However, in nature microbial activity is mainly associated with surfaces where bacteria form highly structured and cooperative consortia whi... |
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N-Acylhomoserine lactones are potent neutrophil chemoattractants that act via calcium mobilization and actin remodeling.
J. Leukoc. Biol. 91(1) , 15-26, (2012) In gram-negative bacteria, cell-cell communication based on HSL QS molecules is known to coordinate the production of virulence factors and biofilms. These bacterial signals can also modulate human immune cell behavior. Using a Transwell migration assay, we f... |
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N-acylhomoserine lactone regulates violacein production in Chromobacterium violaceum type strain ATCC 12472.
FEMS Microbiol. Lett. 279 , 124-130, (2008) In tests, Chromobacterium violaceum ATCC 12472 produced several N-acyl-L-homoserine lactones (AHLs). Of these, N-(3-hydroxydecanoyl)-L-homoserine lactone was dominant, and controlled violacein production by quorum sensing. Strain VIR07, an AHL-deficient mutan... |
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Quenching of acyl-homoserine lactone-dependent quorum sensing by enzymatic disruption of signal molecules.
Acta Biochim. Pol. 56 , 1-16, (2009) Many Gram-positive and Gram-negative bacteria communicate using small diffusible signal molecules called autoinducers. This process, known as quorum sensing (QS), links cell density to the expression of genes as diverse as those associated with virulence fact... |
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Manipulation of quorum sensing regulation in Pseudomonas fluorescens NCIMB 10586 to increase mupirocin production.
Appl. Microbiol. Biotechnol. 90 , 1017-1026, (2011) Transcription of the 74 kb Pseudomonas fluorescens mupirocin [pseudomonic acid (PA)] biosynthesis cluster depends on quorum sensing-dependent regulation via the LuxI/LuxR homologues MupI/MupR. To facilitate analysis of novel PAs from pathway mutants, we inves... |