Acetyl-(N-Me-Leu17,N-Me-Phe19)-Amyloid β-Protein (16-20) amide trifluoroacetate salt

Acetyl-(N-Me-Leu17,N-Me-Phe19)-Amyloid β-Protein (16-20) amide trifluoroacetate salt Structure
Acetyl-(N-Me-Leu17,N-Me-Phe19)-Amyloid β-Protein (16-20) amide trifluoroacetate salt structure
Common Name Acetyl-(N-Me-Leu17,N-Me-Phe19)-Amyloid β-Protein (16-20) amide trifluoroacetate salt
CAS Number 461640-33-5 Molecular Weight 835.95200
Density N/A Boiling Point N/A
Molecular Formula C41H60F3N7O8 Melting Point N/A
MSDS USA Flash Point N/A

Design and characterization of a membrane permeable N-methyl amino acid-containing peptide that inhibits Abeta1-40 fibrillogenesis.

J. Pept. Res. 60 , 37-55, (2002)

Alzheimer's disease, Huntington's disease and prion diseases are part of a growing list of diseases associated with formation of beta-sheet containing fibrils. In a previous publication, we demonstrated that the self-association of the Alzheimer's beta-amyloi...

Probing the role of backbone hydrogen bonding in beta-amyloid fibrils with inhibitor peptides containing ester bonds at alternate positions.

Biochemistry 42 , 475-485, (2003)

Protein-protein interactions are frequently mediated by stable, intermolecular beta-sheets. A number of cytokines and the HIV Protease, for example, dimerize through beta-sheet motifs. Evidence also suggests that the macromolecular assemblies of peptides and ...