4-Cyclohexyl-1-butanol

4-Cyclohexyl-1-butanol Structure
4-Cyclohexyl-1-butanol structure
Common Name 4-Cyclohexyl-1-butanol
CAS Number 4441-57-0 Molecular Weight 156.26500
Density 0.895g/cm3 Boiling Point 233.5ºC at 760mmHg
Molecular Formula C10H20O Melting Point N/A
MSDS USA Flash Point 108.9ºC

Is a nitrogen atom an important pharmacophoric element in sigma ligand binding?

Bioorg. Med. Chem. 8(8) , 2105-11, (2000)

A lingering question in sigma receptor ligand development is whether a nitrogen atom serves as an important pharmacophoric element in binding affinity. To address this question, we have synthesized several phenylalkylpiperidines and phenylalkylpiperazines and...