7-Deaza-2′-deoxyguanosine 5′-triphosphate

7-Deaza-2′-deoxyguanosine 5′-triphosphate Structure
7-Deaza-2′-deoxyguanosine 5′-triphosphate structure
Common Name 7-Deaza-2′-deoxyguanosine 5′-triphosphate
CAS Number 101515-08-6 Molecular Weight 512.12600
Density 2.48 g/cm3 Boiling Point 907.1ºC at 760 mmHg
Molecular Formula C11H16LiN4O13P3 Melting Point N/A
MSDS USA Flash Point 502.4ºC

Serotonin transporter (5-HTTLPR) and norepinephrine transporter (NET) gene polymorphisms: susceptibility and treatment response of electroconvulsive therapy in treatment resistant depression.

Neurosci. Lett. 590 , 116-20, (2015)

Serotonin transporter (5-HTTLPR) and norepinephrine transporter (NET182C) polymorphisms are associated with susceptibility and treatment response in major depressive disorder (MDD). Thus, we examined association between these polymorphisms and susceptibility ...

5-HTTLPR genotype, asthma, diabetes and late-life depression in an older French population.

Int. J. Geriatr. Psychiatry 30 , 1017-22, (2015)

Associations between environmental risk factors and depression have been reported to be stronger in people with the S allele of the S/L polymorphism in the serotonin transporter gene-linked promoter region (5-HTTLPR); however, most studies have focused on adv...

Clinicopathologic report of ocular involvement in ALS patients with C9orf72 mutation.

Amyotroph. Lateral Scler. Frontotemporal Degener. 15(7-8) , 569-80, (2014)

Our objective was to present clinicopathologic evidence of anterior visual pathway involvement in patients with amyotrophic lateral sclerosis (ALS) secondary to a C9orf72 mutation. Two related patients from an extended pedigree with ALS and GGGGCC hexanucleot...

The luminal progenitor compartment of the normal human mammary gland constitutes a unique site of telomere dysfunction.

Stem Cell Reports 1 , 28-37, (2013)

Telomeres are essential for genomic integrity, but little is known about their regulation in the normal human mammary gland. We now demonstrate that a phenotypically defined cell population enriched in luminal progenitors (LPs) is characterized by unusually s...

The serotonin transporter genotype modulates the relationship between early stress and adult suicidality in bipolar disorder.

Bipolar Disord. 16(8) , 857-66, (2014)

Bipolar disorder (BD) is associated with a higher risk of suicide and with worse early life stress. A serotonin (5-hydroxytryptamine; 5-HT) transporter-linked polymorphic region (5-HTTLPR) has been shown to influence the relationship between stress and the ri...

C9orf72 mutation is rare in Alzheimer's disease, Parkinson's disease, and essential tremor in China.

Front. Cell. Neurosci. 7 , 164, (2013)

GGGGCC repeat expansions in the C9orf72 gene have been identified as a major contributing factor in patients with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Given the overlapping of clinical phenotypes and pathological characterist...

Comparative determination of HIV-1 co-receptor tropism by Enhanced Sensitivity Trofile, gp120 V3-loop RNA and DNA genotyping.

Retrovirology 7 , 56, (2010)

Trofile is the prospectively validated HIV-1 tropism assay. Its use is limited by high costs, long turn-around time, and inability to test patients with very low or undetectable viremia. We aimed at assessing the efficiency of population genotypic assays base...

Novel regulator MphX represses activation of phenol hydroxylase genes caused by a XylR/DmpR-type regulator MphR in Acinetobacter calcoaceticus.

PLoS ONE 6 , e17350, (2011)

Acinetobacter calcoaceticus PHEA-2 utilizes phenol as its sole carbon and energy source and has a multi-component phenol hydroxylase-encoding gene operon (mphKLMNOP) for phenol degradation. Two additional genes, mphR and mphX, were found upstream and downstre...

The presence of telomere fusion in sporadic colon cancer independently of disease stage, TP53/KRAS mutation status, mean telomere length, and telomerase activity.

Neoplasia 16(10) , 814-23, (2014)

Defects in telomere maintenance can result in telomere fusions that likely play a causative role in carcinogenesis by promoting genomic instability. However, this proposition remains to be fully understood in human colon carcinogenesis. In the present study, ...

Serotonin transporter genotype, morning cortisol and subsequent depression in adolescents.

Br. J. Psychiatry 195 , 39-45, (2009)

The short (s) allele of the serotonin transporter gene promoter (5-HTTLPR) may be associated with exposure to social adversities and the subsequent onset of depressive illness in adulthood.To test in adolescents at high risk for depression whether the short '...