![]() 7-Deaza-2′-deoxyguanosine 5′-triphosphate structure
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Common Name | 7-Deaza-2′-deoxyguanosine 5′-triphosphate | ||
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CAS Number | 101515-08-6 | Molecular Weight | 512.12600 | |
Density | 2.48 g/cm3 | Boiling Point | 907.1ºC at 760 mmHg | |
Molecular Formula | C11H16LiN4O13P3 | Melting Point | N/A | |
MSDS | USA | Flash Point | 502.4ºC |
Serotonin transporter (5-HTTLPR) and norepinephrine transporter (NET) gene polymorphisms: susceptibility and treatment response of electroconvulsive therapy in treatment resistant depression.
Neurosci. Lett. 590 , 116-20, (2015) Serotonin transporter (5-HTTLPR) and norepinephrine transporter (NET182C) polymorphisms are associated with susceptibility and treatment response in major depressive disorder (MDD). Thus, we examined association between these polymorphisms and susceptibility ... |
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5-HTTLPR genotype, asthma, diabetes and late-life depression in an older French population.
Int. J. Geriatr. Psychiatry 30 , 1017-22, (2015) Associations between environmental risk factors and depression have been reported to be stronger in people with the S allele of the S/L polymorphism in the serotonin transporter gene-linked promoter region (5-HTTLPR); however, most studies have focused on adv... |
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Clinicopathologic report of ocular involvement in ALS patients with C9orf72 mutation.
Amyotroph. Lateral Scler. Frontotemporal Degener. 15(7-8) , 569-80, (2014) Our objective was to present clinicopathologic evidence of anterior visual pathway involvement in patients with amyotrophic lateral sclerosis (ALS) secondary to a C9orf72 mutation. Two related patients from an extended pedigree with ALS and GGGGCC hexanucleot... |
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The luminal progenitor compartment of the normal human mammary gland constitutes a unique site of telomere dysfunction.
Stem Cell Reports 1 , 28-37, (2013) Telomeres are essential for genomic integrity, but little is known about their regulation in the normal human mammary gland. We now demonstrate that a phenotypically defined cell population enriched in luminal progenitors (LPs) is characterized by unusually s... |
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The serotonin transporter genotype modulates the relationship between early stress and adult suicidality in bipolar disorder.
Bipolar Disord. 16(8) , 857-66, (2014) Bipolar disorder (BD) is associated with a higher risk of suicide and with worse early life stress. A serotonin (5-hydroxytryptamine; 5-HT) transporter-linked polymorphic region (5-HTTLPR) has been shown to influence the relationship between stress and the ri... |
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C9orf72 mutation is rare in Alzheimer's disease, Parkinson's disease, and essential tremor in China.
Front. Cell. Neurosci. 7 , 164, (2013) GGGGCC repeat expansions in the C9orf72 gene have been identified as a major contributing factor in patients with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Given the overlapping of clinical phenotypes and pathological characterist... |
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Comparative determination of HIV-1 co-receptor tropism by Enhanced Sensitivity Trofile, gp120 V3-loop RNA and DNA genotyping.
Retrovirology 7 , 56, (2010) Trofile is the prospectively validated HIV-1 tropism assay. Its use is limited by high costs, long turn-around time, and inability to test patients with very low or undetectable viremia. We aimed at assessing the efficiency of population genotypic assays base... |
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Novel regulator MphX represses activation of phenol hydroxylase genes caused by a XylR/DmpR-type regulator MphR in Acinetobacter calcoaceticus.
PLoS ONE 6 , e17350, (2011) Acinetobacter calcoaceticus PHEA-2 utilizes phenol as its sole carbon and energy source and has a multi-component phenol hydroxylase-encoding gene operon (mphKLMNOP) for phenol degradation. Two additional genes, mphR and mphX, were found upstream and downstre... |
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The presence of telomere fusion in sporadic colon cancer independently of disease stage, TP53/KRAS mutation status, mean telomere length, and telomerase activity.
Neoplasia 16(10) , 814-23, (2014) Defects in telomere maintenance can result in telomere fusions that likely play a causative role in carcinogenesis by promoting genomic instability. However, this proposition remains to be fully understood in human colon carcinogenesis. In the present study, ... |
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Serotonin transporter genotype, morning cortisol and subsequent depression in adolescents.
Br. J. Psychiatry 195 , 39-45, (2009) The short (s) allele of the serotonin transporter gene promoter (5-HTTLPR) may be associated with exposure to social adversities and the subsequent onset of depressive illness in adulthood.To test in adolescents at high risk for depression whether the short '... |