Benfluorex hydrochloride
Benfluorex hydrochloride structure
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Common Name | Benfluorex hydrochloride | ||
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| CAS Number | 23642-66-2 | Molecular Weight | 387.82400 | |
| Density | 1.183g/cm3 | Boiling Point | 420.5ºC at 760mmHg | |
| Molecular Formula | C19H21ClF3NO2 | Melting Point | 158-159?C | |
| MSDS | Chinese USA | Flash Point | 208.1ºC | |
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[Benfluorex and valvular heart disease].
Presse Med. 40(11) , 1008-16, (2011) Benfluorex is responsible of restrictive organic valvular regurgitations via one of its metabolites, the norfenfluramine. It has been withdrawn from the european market in June 2010. In France, about five millions of people have been exposed to benfluorex sin... |
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[About the settlement of litigations concerning the harm caused by benfluorex (Mediator®)].
Presse Med. 42(4 Pt 1) , 411-8, (2013) Since September 1st 2011, the National Bureau for Compensation of Medical Accidents represents a unique portal for out-of-court settlement of litigations concerning the harm caused by benfluorex. In December 2012, its official record is as follows: 7627 patie... |
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[Reform Act on safety of drug and health products in France: announcement effect, strengthening or upheaval?].
Therapie. 67(1) , 1-10, (2012) In France, the Médiator(®) scandal and the trauma it has created, are the source of Law n° 2011-2012 of 29 December 2011 on strengthening safety of drug and health products, intended by the Ministry of Labour, Employment and Health, adopted by the National As... |
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Mediator scandal engulfs French compensation body.
Lancet 381(9880) , 1803, (2013)
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European legislators tighten rules on drug safety.
BMJ 345 , e6260, (2012)
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Can benfluorex induce congenital malformations?
Diabetes Metab. 38(4) , 373-4, (2012)
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Top adviser at the European Medicines Agency quits suddenly.
BMJ 344 , e2641, (2012)
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Appetite suppressant was probably responsible for 1300 deaths, study shows.
BMJ 344 , e996, (2012)
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European drug regulator is being investigated by fraud agency.
BMJ 343 , d7283, (2011)
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How can benfluorex-related heart valve disease be identified by echocardiography?
Arch. Cardiovasc. Dis. 104(10) , 489-92, (2011)
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