4-Methylumbelliferyl phosphate
4-Methylumbelliferyl phosphate structure
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Common Name | 4-Methylumbelliferyl phosphate | ||
|---|---|---|---|---|
| CAS Number | 3368-04-5 | Molecular Weight | 240.149 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 513.6±60.0 °C at 760 mmHg | |
| Molecular Formula | C10H9O6P | Melting Point | 215-218 °C | |
| MSDS | Chinese USA | Flash Point | 264.4±32.9 °C | |
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Fungal recognition enhances mannose receptor shedding through dectin-1 engagement.
J. Biol. Chem. 286(10) , 7822-9, (2011) The mannose receptor (MR) is an endocytic type I membrane molecule with a broad ligand specificity that is involved in both hemostasis and pathogen recognition. Membrane-anchored MR is cleaved by a metalloproteinase into functional soluble MR (sMR) composed o... |
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Isolation and characterization of Xenopus soluble epoxide hydrolase.
Biochim. Biophys. Acta 1841(7) , 954-62, (2014) Soluble epoxide hydrolase (sEH) contributes to cell growth, but the contribution of sEH to embryonic development is not well understood. In this study, Xenopus sEH cDNA was isolated from embryos of Xenopus laevis. The Xenopus sEH was expressed in Escherichia ... |
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Hypoxic preconditioning of mesenchymal stromal cells induces metabolic changes, enhances survival, and promotes cell retention in vivo.
Stem Cells 33 , 1818-28, (2015) Mesenchymal stem cells/multipotent stromal cells (MSCs) are promising therapeutics for a variety of conditions. However, after transplantation, cell retention remains extremely challenging. Given that many hypoxic signals are transitory and that the therapeut... |
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The metabolism of lysophosphatidic acids by allelic variants of human soluble epoxide hydrolase.
Drug Metab. Pharmacokinet. 30(1) , 75-81, (2015) Lysophosphatidic acids (LPAs) are phospholipids which have many physiological and pathophysiological functions. The human soluble epoxide hydrolase (sEH) plays a role in the metabolism of xenobiotics through its metabolism of aromatic hydrocarbon epoxides suc... |
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Quality assurance in immunoassay performance--comparison of different enzyme immunoassays for the determination of caffeine in consumer products.
Anal. Bioanal. Chem 405(5) , 1601-11, (2013) Enzyme immunoassays with optical detection are amongst the most widely used bioanalytical tools. We defined seven parameters for the quality assessment of immunoassays that were addressed in a systematic study of direct and indirect immunoassays, using the en... |
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Extracellular enzyme activities during slow sand filtration in a water recharge plant.
Water Res. 35(10) , 2484-8, (2001) Activities of the extracellular enzymes beta-glucosidase and phosphatase and bacterial densities were investigated during the filtration process at several sites in a groundwater recharge plant at the Ruhr river (Hengsen recharge plant in Schwerte. Germany). ... |
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Fluorescence enhancement aided by metal ion displacement.
Biosens. Bioelectron. 80 , 237-42, (2016) Immunosensors are one of the most common platform used in clinical laboratories, in particular the class based on Enzyme Linked Fluorescent Assays (ELFA) takes advantage of the amplification step of the enzyme, usually the alkaline phosphatase, that catalyzes... |
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Application of intracellular alkaline phosphatase activity measurement in detection of neutrophil adherence in vitro.
Mediators Inflamm. 2006(4) , 19307, (2006) We have proposed the use of the fluorimetric method with 4-methylumbelliferyl phosphate (4-MUP) specific substrate for the alkaline phosphatase determination in the neutrophil adhesion assay. We provide evidence that the endogenous neutrophil alkaline phospha... |
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T3D-959: A Multi-Faceted Disease Remedial Drug Candidate for the Treatment of Alzheimer's Disease.
J. Alzheimers Dis. 51 , 123-38, (2016) T3D-959, a dual PPAR-δ/PPAR γ nuclear receptor agonist and former diabetes drug candidate, has been repositioned as an Alzheimer's disease (AD)-modifying therapy.This study examines the effectiveness and mechanisms of T3D-959's therapeutic effects using in vi... |
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Tobacco Smoke Exposure Impairs Brain Insulin/IGF Signaling: Potential Co-Factor Role in Neurodegeneration.
J. Alzheimers Dis. 50 , 373-86, (2016) Human studies suggest tobacco smoking is a risk factor for cognitive impairment and neurodegeneration, including Alzheimer's disease (AD). However, experimental data linking tobacco smoke exposures to underlying mediators of neurodegeneration, including impai... |