ETI
ETI structure
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Common Name | ETI | ||
|---|---|---|---|---|
| CAS Number | 13488-22-7 | Molecular Weight | 300.44 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 473.8±40.0 °C at 760 mmHg | |
| Molecular Formula | C20H28O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 221.9±22.0 °C | |
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Nonsteroidal anti-inflammatory drugs, short-chain fatty acids, and reactive oxygen metabolism in human colorectal cancer cells.
Biochim. Biophys. Acta 1401(3) , 277-88, (1998) Nonsteroidal anti-inflammatory drugs (NSAIDs) and short-chain fatty acids are effective suppressors of colorectal cancer that may work in part by accentuating apoptosis of transformed cells. Since reactive oxygen species (ROS) can play an important role in re... |
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Eicosatetraynoic and arachidonic acid-induced changes in cell membrane fluidity consonant with differences in computer-aided design-structures.
Biochim. Biophys. Acta 1105(2) , 285-90, (1992) ETYA (5,8,11,14-eicosatetraynoic acid), a competitive analogue of arachidonic acid (AA), inhibits the proliferation of U937 (human monoblastoid) and PC3 (human prostate) cancer cells, without the overt cytotoxicity associated with AA at similar concentrations... |
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Chlamydia pneumoniae induces nitric oxide synthase and lipoxygenase-dependent production of reactive oxygen species in platelets. Effects on oxidation of low density lipoproteins.
Thromb. Haemost. 94(2) , 327-35, (2005) There is increasing evidence that Chlamydia pneumoniae is linked to atherosclerosis and thrombosis. In this regard, we have recently shown that C. pneumoniae stimulates platelet aggregation and secretion, which may play an important role in the progress of at... |
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Indomethacin inhibits bone resorption and lysosomal enzyme release from bone in organ culture.
Scand. J. Rheumatol. 9(3) , 149-56, (1980) The effect of indomethacin on bone resorption was studied in an organ culture system, using calvarial bones from 6--7-day-old mice. It was found that indomethacin inhibited spontaneous bone resorption, as estimated by decreased release of 45Ca, Ca2+ and Pi. I... |
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Mechanical stretch reveals different components of endothelial-mediated vascular tone in rat aortic strips.
Br. J. Pharmacol. 131(7) , 1355-62, (2000) 1. Since the role of mechanical stretches in vascular tone regulation is poorly understood, we studied how stretch can influence endothelial tone. 2. Isometric contractions of isolated rat aortic helical strips were recorded. The resting tension was set at 0.... |
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Eicosatetraynoic and eicosatriynoic acids, lipoxygenase inhibitors, block meiosis via antioxidant action.
Am. J. Physiol. Cell Physiol. 278(4) , C646-50, (2000) We previously showed that nordihydroguaiaretic acid (NDGA) and other antioxidants inhibit the resumption of meiosis in oocyte-cumulus complexes (OCC) and denuded oocytes (DO). Because NDGA is well known to be an inhibitor of lipoxygenases (LOX), we assessed w... |
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Relative potencies of several non-steroidal anti-inflammatory drugs against soya bean 15-lipoxygenase.
Br. J. Dermatol. 109 Suppl 25 , 120-3, (1983) The 15-lipoxygenase from soya bean has been claimed to represent a rapid assay procedure for drugs and chemical agents that inhibit other lipoxygenase products (Kingston, 1981). Although the exact role of products derived from skin lipoxygenase enzymes is not... |
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Inhibition of mammalian hepatic glutathione S-transferases by acetylenic fatty acids.
Toxicol. Lett. 73(2) , 157-65, (1994) Micromolar concentrations of 2 classical inhibitors of lipoxygenase, 5,8,11-eicosatriynoic acid (ETI) and 5,8,11,14-eicosatetraynoic acid (ETYA), were found to cause a significant inhibition of the mixture of isozymes of affinity purified rat and human liver ... |
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Control of the expression of interleukin-2 activity.
Cell. Immunol. 73(1) , 106-14, (1982)
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Effect of essential fatty acid deficiency on the fatty acid composition and arachidonic acid levels in rat maxillae and mandibles.
Calcif. Tissue Int. 55(3) , 169-72, (1994) The fatty acid composition of total lipids and total phospholipids of maxillae and mandibles of rats fed an essential fatty acid-deficient (EFAD), marginally FAD (MEFAD), and a control diet was determined. Patterns typical of an EFA deficiency such as a decre... |