1-(diazomethyl)pyrene
1-(diazomethyl)pyrene structure
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Common Name | 1-(diazomethyl)pyrene | ||
|---|---|---|---|---|
| CAS Number | 78377-23-8 | Molecular Weight | 242.27500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H10N2 | Melting Point | 112ºC | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Application of capillary electrophoresis with laser-induced fluorescence detection for routine determination of methylmalonic acid in human serum.
Anal. Chem. 67(5) , 812-9, (1995) Methylmalonic acid (MMA) in serum is an established marker of cobalamin deficiency. MMA and other short-chain dicarboxylic acids react with 1-pyrenyldiazomethane to form stable, highly fluorescent 1-pyrenylmethyl monoesters. We have analyzed these esters in h... |
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Automated assay of methylmalonic acid in serum and urine by derivatization with 1-pyrenyldiazomethane, liquid chromatography, and fluorescence detection.
Clin. Chem. 39(3) , 392-9, (1993) Determination of methylmalonic acid (MMA) in serum has been established as an accurate test for the diagnosis of cobalamin deficiency. We describe here the development and performance of a liquid-chromatographic assay of MMA in blood and urine. The assay is b... |
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[Highly effective separation and highly sensitive detection for clinical chemistry and biochemistry].
Yakugaku Zasshi 118(2) , 31-50, (1998) Highly effective separation and highly sensitive detection reagents for clinical chemistry and biochemistry were developed and their applications were investigated. The sensitive detection of carboxylic acids was accomplished using 9-anthryldiazomethane (ADAM... |
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Investigation of derivatization reagents for the analysis of diarrhetic shellfish poisoning toxins by liquid chromatography with fluorescence detection.
Nat. Toxins 2(5) , 302-11, (1994) Several derivatization reagents for the conversion of okadaic acid and related DSP toxins to fluorescent derivatives for analysis by liquid chromatography have been examined, viz: 9-anthryldiazomethane (ADAM), 1-pyrenyldiazomethane (PDAM), 4-diazomethyl-7-met... |
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S-carboxymethyl-L-cysteine and it (R/S)-S-oxides in beagle dog plasma and hepatic cytosol.
Xenobiotica 45 , 1047-53, (2015) 1. Incubation of beagle hepatic cytosol, under conditions promoting phenylalanine hydroxylase activity, led to the formation of the sulfoxide derivatives of S-carboxymethyl-L-cysteine, N-acetyl-S-carboxymethyl-L-cysteine, S-methyl-L-cysteine and N-acetyl-S-me... |
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Headspace solid-phase microextraction with 1-pyrenyldiazomethane in-fibre derivatisation for analysis of faecal short-chain fatty acids.
J. Chromatogr. B. Biomed. Sci. Appl. 730(1) , 113-22, (1999) Short chain fatty acids (SFCAs) are nutritionally important products of colonic bacteria. Their analysis in faeces is problematic. We report a headspace solid-phase microextraction procedure in which faecal SCFAs are derivatised on the fibre in-situ with 1-py... |
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Derivatization with 1-pyrenyldiazomethane enhances ionization of glycopeptides but not peptides in matrix-assisted laser desorption/ionization mass spectrometry.
Anal. Chem. 82(20) , 8738-43, (2010) Glycoproteomics holds the promise of new advances in medical technology. However, mass spectrometry has limitations for the structural determination of glycosylated peptides because the hydrophilic nature of the oligosaccharide moiety in glycopeptides is disa... |
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Liquid chromatographic determination of biotin by using 1-pyrenyldiazomethane as a pre-column fluorescent labelling reagent.
J. Chromatogr. A. 456(2) , 421-6, (1988)
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Tumor necrosis factor-induced release of endogenous fatty acids analyzed by a highly sensitive high-performance liquid chromatography method.
J. Lipid Res. 38(9) , 1913-22, (1997) A highly sensitive method to determine agonist-induced release of endogenous fatty acids from cells in culture was developed using high-performance liquid chromatography and fluorescence detection. Fatty acids were selectively derivatized with 1-pyrenyldiazom... |
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Analysis of cardiolipin in human muscle biopsy.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 831(1-2) , 63-71, (2006) Cardiolipin is a phospholipid that is specific to the inner mitochondrial membrane and essential for numerous mitochondrial functions. Accordingly, a quantitative assay for cardiolipin can be a valuable aspect of assessing mitochondrial content and functional... |