![]() 5-Doxyl stearic acid structure
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Common Name | 5-Doxyl stearic acid | ||
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CAS Number | 29545-48-0 | Molecular Weight | 384.57300 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C22H42NO4 | Melting Point | N/A | |
MSDS | Chinese USA | Flash Point | N/A |
Spin-probe investigations of head group behavior in aqueous dispersions of a nonionic amphiphilic compound.
Lipids 42(5) , 457-62, (2007) Head group behavior of nonionic amphiphilic compound, (poly(oxyethylene) hydrogenated castor oil, HCO), in aqueous dispersions were investigated by EPR (electron paramagnetic resonance) in conjunction with a modern slow-tumbling simulation. The aliphatic spin... |
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Fenofibrate subcellular distribution as a rationale for the intracranial delivery through biodegradable carrier.
J. Physiol. Pharmacol. 66 , 233-47, (2015) Fenofibrate, a well-known normolipidemic drug, has been shown to exert strong anticancer effects against tumors of neuroectodermal origin including glioblastoma. Although some pharmacokinetic studies were performed in the past, data are still needed about the... |
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Determining radical penetration into membranes using ESR splitting constants.
Free Radic. Biol. Med. 49(3) , 427-36, (2010) Determination of the depth of radical penetration into a lipid membrane is critical to the understanding of the role membranes play in radical attack. We have previously studied radical penetration into lipid bilayers using novel lipophilic spin traps and a c... |
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Electron paramagnetic resonance study of lipid and protein membrane components of erythrocytes oxidized with hydrogen peroxide.
Braz. J. Med. Biol. Res. 45(6) , 473-81, (2012) Electron paramagnetic resonance (EPR) spectroscopy of spin labels was used to monitor membrane dynamic changes in erythrocytes subjected to oxidative stress with hydrogen peroxide (H(2)O(2)). The lipid spin label, 5-doxyl stearic acid, responded to dramatic r... |
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EPR studies on the organization of self-assembled spin-labeled organic monolayers adsorbed on GaAs.
Phys. Chem. Chem. Phys. 7(3) , 524-9, (2005) Characterizing the structure and dynamic properties of a single monolayer is a challenge due to the minute amount of material that is probed. Here, EPR spectroscopy is used for investigating the spatial and temporal organization of self-assembled monolayers o... |
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The interaction of Fusarium solani pisi cutinase with long chain spin label esters.
Biochemistry 45(30) , 9163-71, (2006) We here present a study of the interaction between the Fusarium solani pisi cutinase mutant S120A and spin-labeled 4,4-dimethyloxazoline-N-oxyl-(DOXYL)-stearoyl-glycerol substrates in a micellar system. The interaction is detected by NMR measuring changes in ... |
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Investigating the structural and dynamic properties of n-doxylstearic acid in magnetically-aligned phospholipid bilayers by X-band EPR spectroscopy.
Chem. Phys. Lipids 133(2) , 151-64, (2005) X-band electron paramagnetic resonance (EPR) spectroscopy has been employed to investigate the dynamic properties of magnetically-aligned phospholipid bilayers (bicelles) based on the molecular order parameters (S(mol)), the hyperfine splitting values and the... |
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Interaction of photosensitizers with liposomes containing unsaturated lipid.
Chem. Phys. Lipids 145(2) , 63-71, (2007) Small unilamellar liposomes were made of dipalmitoyl-phosphatidylcholine and dioleoyl-phosphatidylcholine, and photosensitized by a symmetrically or an asymmetrically substituted glycosilated tetraphenyl-porphyrin derivative. As differential scanning calorime... |
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Influence on intestinal mucous permeation of paclitaxel of absorption enhancers and dosage forms based on electron spin resonance spectroscopy.
Pharmazie 62(5) , 368-71, (2007) The aim of this paper is to investigate the permeation mechanism of the hydrophobic drug, paclitaxel in intestinal membranes of mice in relation to enhancers and preparation factors. The alteration fluidity of lipid and protein in mucous membrane were determi... |
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PEGylated Liposomes as Carriers of Hydrophobic Porphyrins.
J. Phys. Chem. B 119 , 6646-57, (2015) Sterically stabilized liposomes (SSLs) (PEGylated liposomes) are applied as effective drug delivery vehicles. Understanding the interactions between hydrophobic compounds and PEGylated membranes is therefore important to determine the effectiveness of PEGylat... |